Conspectus Cellular senescence can be defined as an irreversible stop** of cell
proliferation that arises in response to various stress signals. Cellular senescence is …

Cellular senescence, a form of terminal cell cycle arrest, is as a key driver of organismal
ageing and an important factor in age-related diseases. Insights into the senescent …

Fluorescent probes are essential for optical imaging and have been extensively employed
for precise cancer diagnosis studies. β-galactosidase (β-gal) serves as a primary biomarker …

The demand for novel, minimally invasive, cost-effective, and easily readable diagnostic
tools, primarily designed for the longitudinal monitoring of diseases and their treatments, has …

β-Galactosidase (β-gal) has emerged as a pivotal biomarker in primary ovarian cancer.
Despite the existence of numerous fluorescent probes for β-gal activity detection, quinone …

Simultaneous detection of multiple biomarkers is crucial to achieve specific and dynamic
analysis of cellular senescence, given its intrinsic high heterogeneity. Current approaches …

Senescence is a crucial hallmark of ageing and a significant contributor to the pathology of
age-related disorders. As committee members of the young International Cell Senescence …

The development of rapidly distributed and retained probes within the kidneys is important
for accurately diagnosing kidney diseases. Although molecular imaging shows the potential …

Les travaux de cette thèse ont porté sur l'ouverture de sultones dans le cadre du
développement de nouveaux agents de contraste polyfluorés amphiphiles pour l'Imagerie …

Abstract According to World Health Organization (WHO) studies, there will be 24 million new
cases of cancer worldwide by 2035. Approximately 30% of these lives could be saved …