Physiology and neurobiology of stress and adaptation: central role of the brain

BS McEwen - Physiological reviews, 2007 - journals.physiology.org
The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …

Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition

MJ Morris, JE Beilharz, J Maniam, AC Reichelt… - Neuroscience & …, 2015 - Elsevier
Abstract Changes in food composition and availability have contributed to the dramatic
increase in obesity over the past 30–40 years in developed and, increasingly, in develo** …

Higher risk of dementia in English older individuals who are overweight or obese

Y Ma, O Ajnakina, A Steptoe… - International journal of …, 2020 - academic.oup.com
Background Several risk factors contribute to dementia, but the role of obesity remains
unclear. This study investigated whether increased body weight or central obesity were …

Western diet consumption and cognitive impairment: links to hippocampal dysfunction and obesity

SE Kanoski, TL Davidson - Physiology & behavior, 2011 - Elsevier
Intake of saturated fats and simple carbohydrates, two of the primary components of a
modern Western diet, is linked with the development of obesity and Alzheimer's Disease …

Effects of high-fat diet exposure on learning & memory

ZA Cordner, KLK Tamashiro - Physiology & behavior, 2015 - Elsevier
The associations between consumption of a high-fat or 'Western'diet and metabolic
disorders such as obesity, diabetes, and cardiovascular disease have long been recognized …

The complex interactions between obesity, metabolism and the brain

RM Uranga, JN Keller - Frontiers in neuroscience, 2019 - frontiersin.org
Obesity is increasing at unprecedented levels globally, and the overall impact of obesity on
the various organ systems of the body is only beginning to be fully appreciated. Because of …

The longer-term impacts of Western diet on human cognition and the brain

H Francis, R Stevenson - Appetite, 2013 - Elsevier
Animal work over the last three decades has generated a convincing body of evidence that a
Western diet–one high in saturated fat and refined carbohydrates (HFS diet)–can damage …

Adipokines: a link between obesity and dementia?

AJ Kiliaan, IAC Arnoldussen, DR Gustafson - The Lancet Neurology, 2014 - thelancet.com
Being overweight or obese, as measured with body-mass index or central adiposity (waist
circumference), and the trajectory of body-mass index over the life course have been …

Hippocampus contributions to food intake control: mnemonic, neuroanatomical, and endocrine mechanisms

SE Kanoski, HJ Grill - Biological psychiatry, 2017 - Elsevier
Food intake is a complex behavior that can occur or cease to occur for a multitude of
reasons. Decisions about where, when, what, and how much to eat are not merely reflexive …

Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high‐fat diet

BP Sampey, AM Vanhoose, HM Winfield… - …, 2011 - Wiley Online Library
Obesity has reached epidemic proportions worldwide and reports estimate that American
children consume up to 25% of calories from snacks. Several animal models of obesity exist …