Non-invasive delivery strategies for biologics
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …
clinical and commercial success, biologics are a rapidly growing class and have become a …
Customized materials-assisted microorganisms in tumor therapeutics
QW Chen, JY Qiao, XH Liu, C Zhang… - Chemical Society …, 2021 - pubs.rsc.org
Microorganisms have been extensively applied as active biotherapeutic agents or drug
delivery vehicles for antitumor treatment because of their unparalleled bio-functionalities …
delivery vehicles for antitumor treatment because of their unparalleled bio-functionalities …
Poly (beta-amino ester) s as gene delivery vehicles: challenges and opportunities
Introduction Gene delivery technologies are being developed for an increasing number of
biomedical applications, with delivery vehicles including viruses and non-viral materials …
biomedical applications, with delivery vehicles including viruses and non-viral materials …
Poly (β‐Amino Esters): synthesis, formulations, and their biomedical applications
Abstract Poly (β‐amino ester)(abbreviated as PBAE or PAE) refers to a polymer synthesized
from an acrylate and an amine by Michael addition and has properties inherent to tertiary …
from an acrylate and an amine by Michael addition and has properties inherent to tertiary …
Improving vaccine and immunotherapy design using biomaterials
Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as
technologies to improve the efficacy of vaccines against infectious disease and …
technologies to improve the efficacy of vaccines against infectious disease and …
Nanocarriers with conjugated antimicrobials to eradicate pathogenic biofilms evaluated in murine in vivo and human ex vivo infection models
Conventional antimicrobials are becoming increasingly ineffective for treating bacterial
infection due to the emergence of multi-drug resistant (MDR) pathogens. In addition, the …
infection due to the emergence of multi-drug resistant (MDR) pathogens. In addition, the …
Bacterial-host interactions: physiology and pathophysiology of respiratory infection
It has long been thought that respiratory infections are the direct result of acquisition of
pathogenic viruses or bacteria, followed by their overgrowth, dissemination, and in some …
pathogenic viruses or bacteria, followed by their overgrowth, dissemination, and in some …
Tailoring biomaterials for vaccine delivery
Y Zhuo, H Zeng, C Su, Q Lv, T Cheng, L Lei - Journal of …, 2024 - Springer
Biomaterials are substances that can be injected, implanted, or applied to the surface of
tissues in biomedical applications and have the ability to interact with biological systems to …
tissues in biomedical applications and have the ability to interact with biological systems to …
[HTML][HTML] Prophylactic vaccine delivery systems against epidemic infectious diseases
C Pan, H Yue, L Zhu, G Ma, H Wang - Advanced drug delivery reviews, 2021 - Elsevier
Prophylactic vaccines have evolved from traditional whole-cell vaccines to safer subunit
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …
Poly (β‐amino esters) based potential drug delivery and targeting polymer; an overview and perspectives
S Iqbal, Y Qu, Z Dong, J Zhao, AR Khan… - European Polymer …, 2020 - Elsevier
Poly (β-amino ester) s (PβAE) s are considered as the most potent alternative to viral
vectors, which has been increasingly proposed for targeting gene delivery, because of their …
vectors, which has been increasingly proposed for targeting gene delivery, because of their …