Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …
Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
personalized approaches to cancer treatment are on the rise. For example, targeted drug …
[HTML][HTML] The extracellular matrix of mycobacterial biofilms: could we shorten the treatment of mycobacterial infections?
P Chakraborty, A Kumar - Microbial cell, 2019 - ncbi.nlm.nih.gov
A number of non-tuberculous mycobacterium species are opportunistic pathogens and
ubiquitously form biofilms. These infections are often recalcitrant to treatment and require …
ubiquitously form biofilms. These infections are often recalcitrant to treatment and require …
Interaction of pattern recognition receptors with Mycobacterium tuberculosis
Tuberculosis (TB) is considered a major worldwide health problem with 10 million new
cases diagnosed each year. Our understanding of TB immunology has become greater and …
cases diagnosed each year. Our understanding of TB immunology has become greater and …
Distribution of reactive oxygen species defense mechanisms across domain bacteria
Bacteria are the most diverse and numerous organisms on the planet, inhabiting
environments from the deep subsurface to particles in clouds. Across this range of …
environments from the deep subsurface to particles in clouds. Across this range of …
Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) forms biofilms harbouring antibiotic-tolerant bacilli in vitro,
but the factors that induce biofilm formation and the nature of the extracellular material that …
but the factors that induce biofilm formation and the nature of the extracellular material that …
Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection
A Bhaskar, M Chawla, M Mehta, P Parikh… - PLoS …, 2014 - journals.plos.org
Mycobacterium tuberculosis (Mtb) survives under oxidatively hostile environments
encountered inside host phagocytes. To protect itself from oxidative stress, Mtb produces …
encountered inside host phagocytes. To protect itself from oxidative stress, Mtb produces …
The oxidative stress network of Mycobacterium tuberculosis reveals coordination between radical detoxification systems
M. tuberculosis (Mtb) survives a hostile environment within the host that is shaped in part by
oxidative stress. The mechanisms used by Mtb to resist these stresses remain ill-defined …
oxidative stress. The mechanisms used by Mtb to resist these stresses remain ill-defined …
Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis
M McGrath, NC Gey van Pittius… - Journal of …, 2014 - academic.oup.com
The emergence and spread of multidrug-resistant strains of Mycobacterium tuberculosis
remains a major concern of tuberculosis control programmes worldwide, as treatment …
remains a major concern of tuberculosis control programmes worldwide, as treatment …
Surveillance-activated defenses block the ROS–induced mitochondrial unfolded protein response
ED Runkel, S Liu, R Baumeister, E Schulze - PLoS genetics, 2013 - journals.plos.org
Disturbance of cellular functions results in the activation of stress-signaling pathways that
aim at restoring homeostasis. We performed a genome-wide screen to identify components …
aim at restoring homeostasis. We performed a genome-wide screen to identify components …