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Innate immunity to Toxoplasma gondii infection
F Yarovinsky - Nature Reviews Immunology, 2014 - nature.com
Toxoplasma gondii is a protozoan parasite of global importance. In the laboratory setting, T.
gondii is frequently used as a model pathogen to study mechanisms of T helper 1 (TH1) cell …
gondii is frequently used as a model pathogen to study mechanisms of T helper 1 (TH1) cell …
Immune response and immunopathology during toxoplasmosis
Toxoplasma gondii is a protozoan parasite of medical and veterinary significance that is
able to infect any warm-blooded vertebrate host. In addition to its importance to public …
able to infect any warm-blooded vertebrate host. In addition to its importance to public …
Type II Toxoplasma gondii KU80 Knockout Strains Enable Functional Analysis of Genes Required for Cyst Development and Latent Infection
BA Fox, A Falla, LM Rommereim, T Tomita… - Eukaryotic …, 2011 - journals.asm.org
ABSTRACT Type II Toxoplasma gondii KU80 knockouts (Δ ku80) deficient in
nonhomologous end joining were developed to delete the dominant pathway mediating …
nonhomologous end joining were developed to delete the dominant pathway mediating …
Marginal zone B cells regulate antigen-specific T cell responses during infection
R Bankoti, K Gupta, A Levchenko… - The Journal of …, 2012 - journals.aai.org
Marginal zone B cells (MZB) participate in the early immune response to several pathogens.
In this study, we show that in μMT mice infected with Leishmania donovani, CD8 T cells …
In this study, we show that in μMT mice infected with Leishmania donovani, CD8 T cells …
Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
Summary Low-dose human interleukin-2 (hIL-2) treatment is used clinically to treat
autoimmune disorders due to the cytokine's preferential expansion of immunosuppressive …
autoimmune disorders due to the cytokine's preferential expansion of immunosuppressive …
Complex immune cell interplay in the gamma interferon response during Toxoplasma gondii infection
CR Sturge, F Yarovinsky - Infection and immunity, 2014 - journals.asm.org
Toxoplasma gondii is an obligate intracellular parasite of clinical importance, especially in
immunocompromised patients. Investigations into the immune response to the parasite …
immunocompromised patients. Investigations into the immune response to the parasite …
Persistence of Toxoplasma gondii in the central nervous system: a fine‐tuned balance between the parasite, the brain and the immune system
Upon infection of humans and animals with Toxoplasma gondii, the parasites persist as
intraneuronal cysts that are controlled, but not eliminated by the immune system. In …
intraneuronal cysts that are controlled, but not eliminated by the immune system. In …
Toxoplasma gondii: CD8 T Cells Cry for CD4 Help
IA Khan, SJ Hwang, M Moretto - Frontiers in cellular and infection …, 2019 - frontiersin.org
Toxoplasma gondii, an apicomplexan parasite, is a pathogenic protozoan that can infect the
central nervous system. In pregnant women, infection can result in congenital problems of …
central nervous system. In pregnant women, infection can result in congenital problems of …
Interferon-gamma-and perforin-mediated immune responses for resistance against Toxoplasma gondii in the brain
Y Suzuki, Q Sa, M Gehman, E Ochiai - Expert reviews in molecular …, 2011 - cambridge.org
Toxoplasma gondii is an obligate intracellular protozoan parasite that causes various
diseases, including lymphadenitis, congenital infection of fetuses and life-threatening …
diseases, including lymphadenitis, congenital infection of fetuses and life-threatening …
Global status of Toxoplasma gondii infection and associated risk factors in people living with HIV
H Safarpour, M Cevik, M Zarean, A Barac… - Aids, 2020 - journals.lww.com
Objective: Toxoplasma infection remains as the most common cause of focal brain lesions
among people living with HIV (PLHIV) despite the decline in opportunistic infections with the …
among people living with HIV (PLHIV) despite the decline in opportunistic infections with the …