Polyphenols: A concise overview on the chemistry, occurrence, and human health

A Durazzo, M Lucarini, EB Souto, C Cicala… - Phytotherapy …, 2019 - Wiley Online Library
This review gives an updated picture of each class of phenolic compounds and their
properties. The most common classification implies the subdivision of phenolics in two main …

Exploring plant metabolic genomics: chemical diversity, metabolic complexity in the biosynthesis and transport of specialized metabolites with the tea plant as a model

J Zhao, P Li, T **a, X Wan - Critical Reviews in Biotechnology, 2020 - Taylor & Francis
The diversity and complexity of secondary metabolites in tea plants contribute substantially
to the popularity of tea, by determining tea flavors and their numerous health benefits. The …

Natural polyphenols in metabolic syndrome: protective mechanisms and clinical applications

S Zhang, M Xu, W Zhang, C Liu, S Chen - International journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) is a chronic disease, including abdominal obesity, dyslipidemia,
hyperglycemia, and hypertension. It should be noted that the occurrence of MetS is closely …

Pentagalloylglucose (PGG): A valuable phenolic compound with functional properties

C Torres-León, J Ventura-Sobrevilla… - Journal of Functional …, 2017 - Elsevier
Abstract 1, 2, 3, 4, 6-Penta-O-Galloyl-β-d-Glucose (PGG) is a hydrolysable tannin that
belongs to the group of gallotannins but also participates in the formation of ellagitannins …

[HTML][HTML] The insulin receptor: an important target for the development of novel medicines and pesticides

X Zhang, X Zhu, X Bi, J Huang, L Zhou - International journal of molecular …, 2022 - mdpi.com
The insulin receptor (IR) is a transmembrane protein that is activated by ligands in insulin
signaling pathways. The IR has been considered as a novel therapeutic target for clinical …

Tannins as hemostasis modulators

N Marcińczyk, A Gromotowicz-Popławska… - Frontiers in …, 2022 - frontiersin.org
The hemostasis system is often affected by complications associated with cardiovascular
diseases, which results in thromboembolic events. Compounds of plant origin and plant …

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma

P Kubatka, M Kello, K Kajo, M Samec… - International journal of …, 2020 - mdpi.com
Comprehensive scientific data provide evidence that isolated phytochemicals or whole plant
foods may beneficially modify carcinogenesis. The aim of this study was to evaluate the …

Targeting cancer cell mitochondria as a therapeutic approach: recent updates

Q Cui, S Wen, P Huang - Future Medicinal Chemistry, 2017 - Taylor & Francis
Mitochondria play a key role in ATP generation, redox homeostasis and regulation of
apoptosis. Due to the essential role of mitochondria in metabolism and cell survival …

Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L‐arginine

M Ginovyan, H Javrushyan… - Cell Biochemistry …, 2024 - Wiley Online Library
Conventional treatment methods are not effective enough to fight the rapid increase in
cancer cases. The interest is increasing in the investigation of herbal sources for the …

Pentagalloyl glucose and its functional role in vascular health: Biomechanics and drug-delivery characteristics

SS Patnaik, DT Simionescu, CJ Goergen… - Annals of biomedical …, 2019 - Springer
Pentagalloyl glucose (PGG) is an elastin-stabilizing polyphenolic compound that has
significant biomedical benefits, such as being a free radical sink, an anti-inflammatory agent …