The domestic dog represents one of the most dramatic long-term evolutionary experiments
undertaken by humans. From a large wolf-like progenitor, unparalleled diversity in …

Background Runs of homozygosity (ROH) have become the state-of-the-art method for
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …

Mammals (class Mammalia) have evolved diverse craniofacial morphology to adapt to a
wide range of ecological niches. However, the genetic and developmental mechanisms …

Background Patterns of homozygosity can be influenced by several factors, such as
demography, recombination, and selection. Using the goat SNP50 BeadChip, we genotyped …

Synopsis “Brachycephaly” is generally considered a phenotype in which the facial part of the
head is pronouncedly shortened. While brachycephaly is characteristic for some domestic …

Introduction Comprehensive genomic resources offer insights into biological features,
including traits/disease-related genetic loci. The current reference genome assembly for the …

Background Cat breeders observed a frequent occurrence of internal hydrocephalus in
Persian cats with extreme brachycephalic head morphology. Objective To investigate a …

Runs of homozygosity (ROH) are important genomic features that manifest when an
individual inherits two haplotypes that are identical by descent. Their length distributions are …

The development of high throughput SNP genoty** technologies has improved the
genetic dissection of simple and complex traits in many species including cats. The …

Persian cats are a popular cat breed worldwide, and especially in the US, Europe and Asia.
This study aimed to describe the demography, common disorders and mortality in Persians …