Glial fibrillary acidic protein (GFAP), a type III intermediate filament, is a marker of mature
astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs) …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder; it is the most
common cause of dementia and has no treatment. It is characterized by two pathological …

One of the hallmark features in the neurodegenerative disorders (NDDs) is the accumulation
of aggregated and/or non-functional protein in the cellular milieu. Post-translational …

Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by
Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament …

Colorectal cancer (CRC) is one of the costliest health problems and ranks second in cancer-
related mortality in developed countries. With the aid of proteomics, many protein …

Autoantibodies directed against citrullinated epitopes of proteins are highly diagnostic of
rheumatoid arthritis (RA), and elevated levels of protein citrullination can be found in the …

ABSTRACT Periodontitis, rheumatoid arthritis (RA), atherosclerosis (AS), and Alzheimer's
disease (AD) are examples of complex human diseases with chronic inflammatory …

Two-dimensional gel electrophoresis was instrumental in the birth of proteomics in the late
1980s. However, it is now often considered as an outdated technique for proteomics—a …

Herpes simplex virus 1 (HSV-1) is a neurotropic virus that remains latent in neuronal cell
bodies but reactivates throughout an individual's life, causing severe adverse reactions …

Glial fibrillary acidic protein (GFAP) is a discriminative blood biomarker for many
neurological diseases, such as traumatic brain injury. Detection of GFAP in buffer solutions …