The control over iron availability is crucial under homeostatic conditions and even more in
the case of an infection. This results from diverse properties of iron: first, iron is an important …

Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

In the phagocytosis field, ROS production by the phagocyte NOX has been associated with
pathogen killing for the last 50 years. Since the discovery of nonphagocyte NOX, numerous …

IN THE 1880s Elie Metchnikoff observed specialized phago-cytic cells ingesting bacteria,
and recognized the importance of phagocytosis as a defense mechanism in multicellular …

Fig 2. Classification of granules in neutrophils. Peroxidase-positive (azurophilic or primary)
granules are characterized by the content of MPO and may be further divided based on their …

Formyl peptide receptors (FPRs) are a small group of seven-transmembrane domain, G
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes …

As the first line of innate immune cells to migrate towards tumour tissue, neutrophils, can
immediately kill abnormal cells and activate long-term specific adaptive immune responses …

Neutrophils play important roles in host defense against all classes of infectious agents but,
paradoxically, they are also involved in the pathology of various inflammatory conditions …

Lactoferrin (LF) is an iron binding glycoprotein that is present in several mucosal secretions.
Many biological functions have been ascribed to LF. One of the functions of LF is the …

Regulated exocytosis of secretory granules or dense-core granules has been examined in
many well-characterized cell types including neurons, neuroendocrine, endocrine, exocrine …