Living in your skin: microbes, molecules, and mechanisms

MH Swaney, LR Kalan - Infection and immunity, 2021 - Am Soc Microbiol
Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …

Microbiomes other than the gut: inflammaging and age-related diseases

A Santoro, J Zhao, L Wu, C Carru, E Biagi… - Seminars in …, 2020 - Springer
During the course of evolution, bacteria have developed an intimate relationship with
humans colonizing specific body sites at the interface with the body exterior and …

New insights into the intrinsic and extrinsic factors that shape the human skin microbiome

PA Dimitriu, B Iker, K Malik, H Leung, WW Mohn… - MBio, 2019 - Am Soc Microbiol
Despite recognition that biogeography and individuality shape the function and composition
of the human skin microbiome, we know little about how extrinsic and intrinsic host factors …

Age-related variation of bacterial and fungal communities in different body habitats across the young, elderly, and centenarians in Sardinia

L Wu, T Zeng, M Deligios, L Milanesi, MGI Langille… - Msphere, 2020 - Am Soc Microbiol
Human body microbes interact with the host, forming microbial communities that are in
continual flux during the aging process. Previous studies have mostly focused on surveying …

Microglial depletion and abnormalities in gut microbiota composition and short-chain fatty acids in mice after repeated administration of colony stimulating factor 1 …

Y Yang, T Ishima, X Wan, Y Wei, L Chang… - European Archives of …, 2022 - Springer
PLX5622, a brain-penetrant highly specific inhibitor of the colony-stimulating factor 1
receptor (CSF1R), is used to eliminate microglia in the brain. Considering the role of …

Decoding the impact of ageing and environment stressors on skin cell communication

AVS Faria, SS Andrade - Biogerontology, 2025 - Springer
The integumentary system serves as a crucial protective barrier and is subject to complex
signaling pathways that regulate its physiological functions. As the body's first line of …

Skin microbiome profile of healthy Cameroonians and Japanese

K Ogai, BC Nana, YM Lloyd, JP Arios, B Jiyarom… - Scientific Reports, 2022 - nature.com
The commensal microbes of the skin have a significant impact on dermal physiology and
pathophysiology. Racial and geographical differences in the skin microbiome are suggested …

Charting host-microbe co-metabolism in skin aging and application to metagenomics data

W Alkema, J Boekhorst, RT Eijlander, S Schnittger… - PloS one, 2021 - journals.plos.org
During aging of human skin, a number of intrinsic and extrinsic factors cause the alteration of
the skin's structure, function and cutaneous physiology. Many studies have investigated the …

Tracing skin aging process: A mini-review of in vitro approaches

S Letsiou - Biogerontology, 2021 - Springer
Skin is a rather complex, yet useful organ of our body. Besides, skin aging is a complicated
process that gains a growing interest as mediates many molecular processes in our body …