Peripheral nerve injury treatments and advances: one health perspective

B Lopes, P Sousa, R Alvites, M Branquinho… - International journal of …, 2022 - mdpi.com
Peripheral nerve injuries (PNI) can have several etiologies, such as trauma and iatrogenic
interventions, that can lead to the loss of structure and/or function impairment. These …

Mesenchymal stem cells (MSCs) as a potential therapeutic strategy in COVID-19 patients: literature research

A Coelho, RD Alvites, MV Branquinho… - Frontiers in cell and …, 2020 - frontiersin.org
In 2019, an outbreak of an unknown coronavirus–SARS-CoV-2–responsible for COVID-19
disease, was first reported in China, and evolved into a pandemic of huge dimensions and …

3D Printed Poly (𝜀-caprolactone)/Hydroxyapatite Scaffolds for Bone Tissue Engineering: A Comparative Study on a Composite Preparation by Melt Blending or …

S Biscaia, MV Branquinho, RD Alvites… - International Journal of …, 2022 - mdpi.com
Bone tissue engineering has been developed in the past decades, with the engineering of
bone substitutes on the vanguard of this regenerative approach. Polycaprolactone-based …

[HTML][HTML] Hybrid scaffolds for bone tissue engineering: Integration of composites and bioactive hydrogels loaded with hDPSCs

AC Sousa, R Alvites, B Lopes, P Sousa, A Moreira… - Biomaterials …, 2025 - Elsevier
Bone tissue regeneration remains a significant challenge in clinical settings due to the
complexity of replicating the mechanical and biological properties of bone environment. This …

Transplantation of nasal olfactory mucosa mesenchymal stem cells benefits Alzheimer's disease

CG Hong, ML Chen, R Duan, X Wang, ZL Pang… - Molecular …, 2022 - Springer
Alzheimer's disease (AD) is a common neurodegenerative disease that contributes to 60–
70% of dementia in elderly people and is currently incurable. Current treatments only relieve …

Combined Use of Chitosan and Olfactory Mucosa Mesenchymal Stem/Stromal Cells to Promote Peripheral Nerve Regeneration In Vivo

RD Alvites, MV Branquinho, AC Sousa… - Stem cells …, 2021 - Wiley Online Library
Peripheral nerve injury remains a clinical challenge with severe physiological and functional
consequences. Despite the existence of multiple possible therapeutic approaches, until …

[HTML][HTML] Achievements and challenges in transplantation of mesenchymal stem cells in otorhinolaryngology

R Kaboodkhani, D Mehrabani… - Journal of Clinical …, 2021 - mdpi.com
Otorhinolaryngology enrolls head and neck surgery in various tissues such as ear, nose,
and throat (ENT) that govern different activities such as hearing, breathing, smelling …

Three‐dimensional‐printed polycaprolactone/polypyrrole conducting scaffolds for differentiation of human olfactory ecto‐mesenchymal stem cells into Schwann cell …

M Entezari, M Mozafari, M Bakhtiyari… - … Research Part A, 2022 - Wiley Online Library
Implantation of a suitable nerve guide conduit (NGC) seeded with sufficient Schwann cells
(SCs) is required to improve peripheral nerve regeneration efficiently. Given the limitations …

[HTML][HTML] In vitro and in vivo characterization of PLLA-316L stainless steel electromechanical devices for bone tissue engineering—A preliminary study

MV Branquinho, SO Ferreira, RD Alvites… - International Journal of …, 2021 - mdpi.com
Bone injuries represent a major social and financial impairment, commonly requiring
surgical intervention due to a limited healing capacity of the tissue, particularly regarding …

[HTML][HTML] Isolation, expansion, and characterization of rat hair follicle stem cells and their secretome: insights into wound healing potential

P Sousa, B Lopes, AC Sousa, A Coelho… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Stem cells are capable of self-renewal and differentiation into various
specialized cells, making them a potential therapeutic option in regenerative medicine. This …