Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke
XY **ong, L Liu, QW Yang - Progress in neurobiology, 2016 - Elsevier
Microglia/macrophages are the major immune cells involved in the defence against brain
damage. Their morphology and functional changes are correlated with the release of danger …
damage. Their morphology and functional changes are correlated with the release of danger …
CD14: Biology and role in the pathogenesis of disease
Z Wu, Z Zhang, Z Lei, P Lei - Cytokine & growth factor reviews, 2019 - Elsevier
Human monocyte differentiation antigen CD14 is a pattern recognition receptor (PRR) that
enhances innate immune responses. CD14 was first identified as a marker of monocytes to …
enhances innate immune responses. CD14 was first identified as a marker of monocytes to …
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
Microglial activation plays central roles in neuroinflammatory and neurodegenerative
diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein …
diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein …
Toll-like receptors and their role in persistent pain
One of the fundamental mechanisms whereby the innate immune system coordinates
inflammatory signal transduction is through Toll-like receptors (TLRs), which function to …
inflammatory signal transduction is through Toll-like receptors (TLRs), which function to …
Understanding extracellular vesicle and nanoparticle heterogeneity: Novel methods and considerations
Extracellular vesicles (EVs) are a heterogeneous population of membrane‐enclosed
nanoparticles released by cells. They play a role in intercellular communication and are …
nanoparticles released by cells. They play a role in intercellular communication and are …
Oxidative stress and neuroinflammation as a pivot in drug abuse. A focus on the therapeutic potential of antioxidant and anti-inflammatory agents and biomolecules
Drug abuse is a major global health and economic problem. However, there are no
pharmacological treatments to effectively reduce the compulsive use of most drugs of abuse …
pharmacological treatments to effectively reduce the compulsive use of most drugs of abuse …
TET2 regulates the neuroinflammatory response in microglia
Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune
cells. Despite the central role for microglia in neuroinflammation and neurodegeneration …
cells. Despite the central role for microglia in neuroinflammation and neurodegeneration …
Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment
It has been hypothesized that selective serotonin reuptake inhibitors (SSRIs), the most
common treatment for major depression, affect mood through changes in immune function …
common treatment for major depression, affect mood through changes in immune function …
Multiple sclerosis and neuroinflammation: the overview of current and prospective therapies
Persistent neuroinflammation is now recognized as a chief pathological component of
practically all neurodegenerative diseases. Neuroinflammation in the central nervous …
practically all neurodegenerative diseases. Neuroinflammation in the central nervous …
Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury
J Yu, Y Zhang, H Ma, R Zeng, R Liu, P Wang, X **… - Molecular brain, 2020 - Springer
Abstract Background N6-methyladenosine (m6A) is the most prevalent post-transcriptional
modification of eukaryotic mRNA. It has been reported that there is a stimulus-dependent …
modification of eukaryotic mRNA. It has been reported that there is a stimulus-dependent …