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Biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder
Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving …
regarded as being in the early stages of a progressive neurodegenerative disease involving …
Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson's disease and other synucleinopathies
Abstract Parkinson's disease (PD), the second most common progressive
neurodegenerative disease, develops and progresses for 10–15 years before the clinical …
neurodegenerative disease, develops and progresses for 10–15 years before the clinical …
Detection of neuron-derived pathological α-synuclein in blood
A Kluge, J Bunk, E Schaeffer, A Drobny, W ** Parkinson disease
IMPORTANCE Nonmotor symptoms of Parkinson disease (PD) often predate the movement
disorder by decades. Currently, there is no blood biomarker to define this prodromal phase …
disorder by decades. Currently, there is no blood biomarker to define this prodromal phase …
Acceptor functionalization via green chemistry enables high‐performance n‐type organic electrochemical transistors for biosensing, memory applications
The organic electrochemical transistor (OECT) is one of the most versatile building blocks
within the bioelectronics device toolbox. While p‐type organic semiconductors have …
within the bioelectronics device toolbox. While p‐type organic semiconductors have …
Neuroimaging and fluid biomarkers in Parkinson's disease in an era of targeted interventions
A major challenge in Parkinson's disease is the variability in symptoms and rates of
progression, underpinned by heterogeneity of pathological processes. Biomarkers are …
progression, underpinned by heterogeneity of pathological processes. Biomarkers are …
Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention
YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …
insidious age-related neurodegenerative disease and is presently considered a global …
Emergence of extracellular vesicles as “liquid biopsy” for neurological disorders: boom or bust
Extracellular vesicles (EVs) have emerged as an attractive liquid biopsy approach in the
diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching …
diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching …