[HTML][HTML] Aging, cancer, and inflammation: the telomerase connection

V Boccardi, L Marano - International Journal of Molecular Sciences, 2024 - mdpi.com
Understanding the complex dynamics of telomere biology is important in the strong link
between aging and cancer. Telomeres, the protective caps at the end of chromosomes, are …

Unraveling the enigma of tumor-associated macrophages: challenges, innovations, and the path to therapeutic breakthroughs

S Shao, H Miao, W Ma - Frontiers in Immunology, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) are integral to the tumor microenvironment (TME),
influencing cancer progression significantly. Attracted by cancer cell signals, TAMs exhibit …

[HTML][HTML] The Impact of Oral Microbiome Dysbiosis on the Aetiology, Pathogenesis, and Development of Oral Cancer

J Talapko, S Erić, T Meštrović, MM Stipetić, M Juzbašić… - Cancers, 2024 - mdpi.com
Simple Summary The problems associated with oral squamous cell carcinoma (OSCC) are
becoming increasingly apparent. Namely, cancer of the oral cavity is the most common …

Therapeutic Modulation of the Microbiome in Oncology: Current Trends and Future Directions

I Saraswat, A Goel - Current Pharmaceutical Biotechnology, 2024 - benthamdirect.com
Cancer is a predominant cause of mortality worldwide, necessitating the development of
innovative therapeutic techniques. The human microbiome, particularly the gut microbiota …

Exploring the microbiome-gut-testis axis in testicular germ cell tumors

S Ciernikova, A Sevcikova, M Mego - Frontiers in Cellular and …, 2025 - frontiersin.org
The microbiome-gut-testis axis has emerged as a significant area of interest in
understanding testicular cancer, particularly testicular germ cell tumors (TGCTs), which …

Biofilm and cancer: interactions and future directions for cancer therapy

E Choi, B Murray, S Choi - International Journal of Molecular Sciences, 2023 - mdpi.com
There is a growing body of evidence supporting the significant role of bacterial biofilms in
the pathogenesis of various human diseases, including cancer. Biofilms are polymicrobial …

The Roles and Interactions of Porphyromonas gingivalis and Fusobacterium nucleatum in Oral and Gastrointestinal Carcinogenesis: A Narrative Review

B Wang, J Deng, V Donati, N Merali, AE Frampton… - Pathogens, 2024 - mdpi.com
Epidemiological studies have spotlighted the intricate relationship between individual oral
bacteria and tumor occurrence. Porphyromonas gingivalis and Fusobacteria nucleatum …

Tumor Microbial Communities and Thyroid Cancer Development—The Protective Role of Antioxidant Nutrients: Application Strategies and Future Directions

F Gorini, A Tonacci - Antioxidants, 2023 - mdpi.com
Thyroid cancer (TC), the most frequent malignancy of the endocrine system, has recorded
an increasing incidence in the last decades. The etiology of TC remains at least partly …

Modulating the gut microbiome in non-small cell lung cancer: Challenges and opportunities

JB Lee, Y Huang, Y Oya, J Nutzinger, YLE Ang, K Sooi… - Lung Cancer, 2024 - Elsevier
Despite the efficacy of immunotherapy in non-small cell lung cancer (NSCLC), the majority
of the patients experience relapse with limited subsequent treatment options. Preclinical …

Intratumour microbiota modulates adrenocortical cancer responsiveness to mitotane

G Cantini, E Niccolai, L Canu… - Endocrine-Related …, 2023 - erc.bioscientifica.com
The infiltrating microbiota represents a novel cellular component of the solid tumour
microenvironment that can influence tumour progression and response to therapy …