Abstract Linoleic acid (LA)(n− 6) and α-linolenic acid (ALA)(n− 3) are essential fatty acids
(EFAs) as they cannot be synthesized by humans or other higher animals. In the human …

We conducted this meta-analysis of double-blind randomized placebo-controlled trials to
estimate the efficacy of omega-3 polyunsaturated fatty acids (PUFAs), especially …

Depression is the most prevalent mental disorder in the world associated with huge socio-
economic consequences. While depressive-related symptoms are well known, the …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

The health benefits of fish oil, and its omega-3 long chain polyunsaturated fatty acid content,
have attracted much scientific attention in the last four decades. Fish oils that contain higher …

Omega-3 polyunsaturated fatty acids (PUFAs) can play important roles in maintaining
mental health and resistance to stress, and omega-3 PUFAs supplementation can display …

Major depressive disorder (MDD) is a complex mental illness with unmet therapeutic needs.
The antidepressant effects of ω–3 polyunsaturated fatty acids (n–3 PUFAs) have been …

Abstract Long-chain (LC) n-3 polyunsaturated fatty acids (n-3 PUFAs), in particular
docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are nutrients involved in …

Inflammation has been identified as one of the main pathophysiological mechanisms
underlying neuropsychiatric and neurodegenerative disorders. Despite the role of …

Alzheimer's disease (AD) and other forms of dementia represent major public health
challenges but effective therapeutic options are limited. Pathological brain aging is …