Publisher Summary Synthetic and naturally occurring antioxidants have a wide variety of
biological actions in rodents, in addition to their primary antioxidant activity. Many of these …

In this review, the role of dietary antioxidants in the prevention of hepatocarcinogenesis is
examined. Both human and animal models are discussed. Vitamin C, vitamin E, and …

The carcinogenicity of low dietary levels of the antioxidants butylated hydroxyanisole (BHA),
caffeic acid, sesamol, 4-methoxyphenol (4-MP) and catechol, known to target the …

Effects of co-administration of food additives and naturally occurring food components were
studied on the activation of mutagens. Male mice (ddY) were given diets containing …

Abstract Correspondence to: **ao-Ou Shu, MD, PhD, Vanderbilt Epidemiology Center, 2525
West End Ave, Ste 600 (IMPH), Nashville, TN 37203-1738 (e-mail: xiao-ou. shu@ vanderbilt …

We examined the immunosuppressive effects of aflatoxin B1 (AFB1), a toxic compound
produced by the Aspergillus flavus, on murine peritoneal macrophages after in vitro pre …

These substances were considered by previous working groups, in December 1971 (IARC,
1972), October 1975 (IARC, 1976) and March 1987 (IARC, 1987a). Since that time new data …

The effects of vitamin C and aloe vera gel extract supplementation on induced
hepatocarcinogenesis in male Sprague-Dawley rats (120–150 g) by diethylnitrosamine …

This prospective study was undertaken to substantiate observations that glutathione (GSH)
inhibits or reverses tumor growth in humans with hepatocellular carcinoma (HCC), a …

Aflatoxin B1 (AFB1), a potent hepatocarcinogen, has been known to impair non-specific and
specific immunity. Macrophages play an important role in host defense against tumors and …