There is growing evidence that chronic inflammation plays a role in both the development
and progression of diabetic retinopathy. There is also evidence that molecules produced as …

Several mechanisms are associated with brain dysfunction during sepsis; one of the most
important are activation of microglia and astrocytes. Activation of glial cells induces changes …

Retinal neurodegenerative disease involves an inflammatory response in the retina
characterized by an increase in inflammatory cytokines and activation of microglia. The …

Activated microglia have been associated with neurodegeneration in patients and in animal
models of Temporal Lobe Epilepsy (TLE), however their precise functions as neurotoxic or …

Sepsis-associated encephalopathy (SAE) is associated with an increased rate of morbidity
and mortality. It is not understood what the exact mechanism is for the brain dysfunction that …

Ischaemic, excitotoxic and traumatic brain injuries have been associated with the
occurrence of epileptic seizures. Microglia, the principal immune cells in the brain, produce …

20% of symptomatic epilepsies are post-traumatic. We examined effect of LPS
preconditioning on epileptogenesis after controlled cortical impact (CCI). LPS (0.01, 0.1 and …

Growing evidence indicates brain inflammation has been involved in the genesis of
seizures. However, the direct effect of acute inflammation on neuronal circuits is not well …

The aim of this study is to reveal the molecular changes accompanying the neuronal hyper‐
excitability during lipopolysaccharide (LPS)‐induced systemic inflammation on rat …

We investigated the effects of lipopolysachharide (LPS) on functional and structural
properties of the blood–brain barrier (BBB) during pentylenetetrazole (PTZ)-induced …