The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

The first suggestion that physical exercise results in free radical-mediated damage to tissues
appeared in 1978, and the past three decades have resulted in a large growth of knowledge …

Reactive oxygen species (ROS) are known mediators of intracellular signaling cascades.
Excessive production of ROS may, however, lead to oxidative stress, loss of cell function …

Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

It is well established that contracting muscles produce both reactive oxygen and nitrogen
species. Although the sources of oxidant production during exercise continue to be debated …

Selenium (Se) is an essential trace element for animals and humans that is obtained from
dietary sources including cereals, grains and vegetables. The Se content of plants varies …

Selenium is generally known as an antioxidant due to its presence in selenoproteins as
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …

The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

Selenium is an essential trace element with known antioxidant properties. Cytosolic
thioredoxin reductase from mammalian cells is a dimeric flavin enzyme comprising a …

Several decades after the discovery of selenium as an essential trace element in vertebrates
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …