Fitting pieces into the puzzle: The impact of titanium-based dental implant surface modifications on bacterial accumulation and polymicrobial infections

RC Costa, BE Nagay, M Bertolini… - Advances in Colloid and …, 2021 - Elsevier
Polymicrobial infection is the main cause of dental implant failure. Although numerous
studies have reported the ability of titanium (Ti) surface modifications to inhibit microbial …

3D bioprinting: A powerful tool to leverage tissue engineering and microbial systems

E Saygili, AA Dogan-Gurbuz, O Yesil-Celiktas, MS Draz - Bioprinting, 2020 - Elsevier
Bioprinting covers the precise deposition of cells, biological scaffolds and growth factors to
produce desired tissue models. The main focus of bioprinting is the creation of functional …

A composite critical-size rabbit mandibular defect for evaluation of craniofacial tissue regeneration

SR Shah, S Young, JL Goldman, JA Jansen… - Nature protocols, 2016 - nature.com
Translational biomaterials targeted toward the regeneration of large bone defects in the
mandible require a preclinical model that accurately recapitulates the regenerative …

Animal models of implant-related low-grade infections. A twenty-year review

AB Lovati, M Bottagisio, E de Vecchi, E Gallazzi… - A Modern Approach to …, 2017 - Springer
The demand for joint replacement and surgical treatment is continuously increasing, thus
representing a clinical burden and a cost for the healthcare system. Among several …

Drug delivery and tissue engineering to promote wound healing in the immunocompromised host: Current challenges and future directions

AM Tatara, DP Kontoyiannis, AG Mikos - Advanced drug delivery reviews, 2018 - Elsevier
As regenerative medicine matures as a field, more promising technologies are being
translated from the benchtop to the clinic. However, many of these strategies are designed …

Surface Topography Steer Soft Tissue Response and Antibacterial Function at the Transmucosal Region of Titanium Implant

M Safaei, H Mohammadi, S Beddu… - International Journal …, 2024 - Taylor & Francis
Metallic dental implants have been extensively used in clinical practice due to their superior
mechanical properties, biocompatibility, and aesthetic outcomes. However, their integration …

Inherently antimicrobial biodegradable polymers in tissue engineering

E Watson, AM Tatara, DP Kontoyiannis… - … Science & Engineering, 2017 - ACS Publications
Many of the strategies currently being explored in the field of tissue engineering involve the
combination of cells and degradable engineered scaffolds for the regeneration of biological …

Contamination of wounds with fecal bacteria in immuno-suppressed mice

L Karner, S Drechsler, M Metzger, P Slezak… - Scientific Reports, 2020 - nature.com
Immunocompromised patients are predisposed to chronically infected wounds. Especially
ulcers in the dorsal region often experience secondary polymicrobial infections. However …

Development and characterization of a rabbit model of compromised maxillofacial wound healing

SL Piotrowski, L Wilson, N Dharmaraj… - … Engineering Part C …, 2019 - liebertpub.com
Background: Tissue engineering technologies aiming to enhance maxillofacial wound
healing are often tested in vivo in preclinical models that do not necessarily reflect the …

Male or female sex: considerations and translational aspects in diabetic foot ulcer research using rodent models

V Rai, DK Agrawal - Molecular and Cellular Biochemistry, 2023 - Springer
Abstract Treatment of nonhealing diabetic foot ulcers (DFUs) is a major clinical concern and
challenge for clinicians. Despite the advancement in treatment strategies, there is no …