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Self-driving laboratories for chemistry and materials science
Self-driving laboratories (SDLs) promise an accelerated application of the scientific method.
Through the automation of experimental workflows, along with autonomous experimental …
Through the automation of experimental workflows, along with autonomous experimental …
The hitchhiker's guide to flow chemistry∥
Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …
stream rather than in a flask. Flow equipment provides chemists with unique control over …
Automating drug discovery
G Schneider - Nature reviews drug discovery, 2018 - nature.com
Small-molecule drug discovery can be viewed as a challenging multidimensional problem in
which various characteristics of compounds—including efficacy, pharmacokinetics and …
which various characteristics of compounds—including efficacy, pharmacokinetics and …
Automation and computer-assisted planning for chemical synthesis
The molecules of today—the medicines that cure diseases, the agrochemicals that protect
our crops, the materials that make life convenient—are becoming increasingly sophisticated …
our crops, the materials that make life convenient—are becoming increasingly sophisticated …
Optimizing chemical reactions with deep reinforcement learning
Deep reinforcement learning was employed to optimize chemical reactions. Our model
iteratively records the results of a chemical reaction and chooses new experimental …
iteratively records the results of a chemical reaction and chooses new experimental …
Next-generation experimentation with self-driving laboratories
The ever-growing demand for advanced functional materials requires disruption of
conventional approaches to experimentation and acceleration of the discovery process …
conventional approaches to experimentation and acceleration of the discovery process …
[HTML][HTML] Machine learning meets continuous flow chemistry: Automated optimization towards the Pareto front of multiple objectives
Automated development of chemical processes requires access to sophisticated algorithms
for multi-objective optimization, since single-objective optimization fails to identify the trade …
for multi-objective optimization, since single-objective optimization fails to identify the trade …
The past, present and potential for microfluidic reactor technology in chemical synthesis
The past two decades have seen far-reaching progress in the development of microfluidic
systems for use in the chemical and biological sciences. Here we assess the utility of …
systems for use in the chemical and biological sciences. Here we assess the utility of …
Why microfluidics? Merits and trends in chemical synthesis
The intrinsic limitations of conventional batch synthesis have hindered its applications in
both solving classical problems and exploiting new frontiers. Microfluidic technology offers a …
both solving classical problems and exploiting new frontiers. Microfluidic technology offers a …
Organic synthesis: march of the machines
SV Ley, DE Fitzpatrick, RJ Ingham… - Angewandte Chemie …, 2015 - Wiley Online Library
Organic synthesis is changing; in a world where budgets are constrained and the
environmental impacts of practice are scrutinized, it is increasingly recognized that the …
environmental impacts of practice are scrutinized, it is increasingly recognized that the …