Several small molecule species formally known primarily as toxic gases have, over the past
20 years, been shown to be endogenously generated signaling molecules. The biological …

Carbon monoxide (CO) has long been known to have dramatic physiological effects on
organisms ranging from bacteria to humans, but recently there have a number of …

This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

A novel nitrite biosensor was developed through a sensing platform consisted of single-layer
graphene nanoplatelet (SLGnP)–protein composite film. SLGnP with the virtues of excellent …

Cytoglobin and neuroglobin are recently discovered members of the globin family. In situ
hybridization localized neuroglobin mainly in brain and retina, while cytoglobin was …

The genome of the nematode Caenorhabditis elegans encodes seven soluble guanylate
cyclases (sGCs)[1]. In mammals, sGCs function as α/β heterodimers activated by gaseous …

Selectivity among NO, CO, and O2 is crucial for the physiological function of most heme
proteins. Although there is a million-fold variation in equilibrium dissociation constants (KD) …

Heme proteins take part in a number of fundamental biological processes, including oxygen
transport and storage, electron transfer, catalysis and signal transduction. The redox …

Heme proteins perform various biological functions ranging from electron transfer, oxygen
binding and transport, catalysis, to signaling. Although adopting proper native states is very …

This work reviews the recent applications of ab initio multireference/multiconfiguration
(MR/MC) electronic structure methods to heme-related systems, involving tetra-, penta-, and …