Importance Malignant primary brain tumors cause more than 15 000 deaths per year in the
United States. The annual incidence of primary malignant brain tumors is approximately 7 …

Gliomas are a diverse group of primary central nervous system tumors that affect both
children and adults. Recent studies have revealed a dynamic cross talk that occurs between …

Primary CNS tumours refer to a heterogeneous group of tumours arising from cells within the
CNS, and can be benign or malignant. Malignant primary brain tumours remain among the …

Development of novel therapies for CNS tumors requires reliable assessment of response
and progression. This requirement has been particularly challenging in neuro-oncology for …

Gliomas are the most common malignant primary brain tumours in adults and cannot usually
be cured with standard cancer treatments. Gliomas show intratumoural and intertumoural …

Between 2010 and 2014, the incidence rate of primary brain tumors in persons (aged> 20
years) was 29.2 per 100,000; in children (aged< 20 years), the rate was 5.81 per 100,000 …

Tumor-related epilepsy (TRE) is a frequent and major consequence of brain tumors.
Management of TRE is required throughout the course of disease and a deep …

Seizures are a frequent complication of adult-type diffuse gliomas, and are often difficult to
control with medications. Gliomas with mutations in isocitrate dehydrogenase 1 or 2 …

Background Brain tumors are one of the leading causes of epilepsy, and brain tumor‐related
epilepsy (BTRE) is recognized as the major cause of intractable epilepsy, resulting in huge …

Simple Summary Diffuse low-grade gliomas (LGG) are relatively uncommon primary brain
cancers. In recent years, the molecular, diagnostic, and therapeutic approaches have …