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[HTML][HTML] Thioredoxin (Trx): A redox target and modulator of cellular senescence and aging-related diseases
B Yang, Y Lin, Y Huang, YQ Shen, Q Chen - Redox biology, 2024 - Elsevier
Thioredoxin (Trx) is a compact redox-regulatory protein that modulates cellular redox state
by reducing oxidized proteins. Trx exhibits dual functionality as an antioxidant and a cofactor …
by reducing oxidized proteins. Trx exhibits dual functionality as an antioxidant and a cofactor …
Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α
Many functional aspects of the protein kinase p38α have been illustrated by more than three
hundred structures determined in the presence of reducing agents. These structures …
hundred structures determined in the presence of reducing agents. These structures …
TrxT and dhd are dispensable for Drosophila brain development but essential for l(3)mbt brain tumour growth
C Molnar, JP Heinen, J Reina, S Llamazares… - EMBO …, 2024 - embopress.org
Expression of the Drosophila cancer-germline (CG), X-linked, head-to-head gene pair TrxT
and dhd is normally germline-specific but becomes upregulated in brain tumours caused by …
and dhd is normally germline-specific but becomes upregulated in brain tumours caused by …
The evolutionarily conserved PhLP3 is essential for sperm development in Drosophila melanogaster
C Petit, E Kojak, S Webster, M Marra, B Sweeney… - Plos one, 2024 - journals.plos.org
Phosducin-like proteins (PhLP) are thioredoxin domain-containing proteins that are highly
conserved across unicellular and multicellular organisms. PhLP family proteins are …
conserved across unicellular and multicellular organisms. PhLP family proteins are …
Three classes of epigenomic regulators converge to hyperactivate the essential maternal gene deadhead within a heterochromatin mini-domain
D Torres-Campana, B Horard, S Denaud… - PLoS …, 2022 - journals.plos.org
The formation of a diploid zygote is a highly complex cellular process that is entirely
controlled by maternal gene products stored in the egg cytoplasm. This highly specialized …
controlled by maternal gene products stored in the egg cytoplasm. This highly specialized …
The Drosophila cancer-germline, head-to-head gene pair TrxT and dhd is dispensable for normal brain development but plays a major role in l (3) malignant brain …
C Molnar, JP Heinen, J Reina, S Llamazares… - bioRxiv, 2023 - biorxiv.org
ABSTRACT Drosophila thioredoxins Deadhead (Dhd) and Thioredoxin-T (TrxT) are
encoded by a head-to-head gene pair in the X chromosome. Akin to human cancer-germline …
encoded by a head-to-head gene pair in the X chromosome. Akin to human cancer-germline …
Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α
M Macias, J Pous, B Baginski, P Martin-Malpartida… - 2023 - researchsquare.com
Many functional aspects of the protein kinase p38α have been illustrated by more than three
hundred structures, covering free forms and complexes with activators, substrates and …
hundred structures, covering free forms and complexes with activators, substrates and …
Epigenetic control of the ovarian transcriptome in Drosophila melanogaster
DT Campana - 2021 - theses.hal.science
Dynamic regulation of the epigenome underlies cellular plasticity and allows cells to
respond to developmental and differentiation programs. Epigenomic effectors can mediate …
respond to developmental and differentiation programs. Epigenomic effectors can mediate …
[HENVISNING][C] Contrôle épigénétique du transcriptome ovarien chez Drosophila melanogaster
CPU VIEIRA-HEDDI, L DI STEFANO, AM MARTINEZ…