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Progress in alternative strategies to combat antimicrobial resistance: Focus on antibiotics
Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR),
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
Phage display derived monoclonal antibodies: from bench to bedside
Monoclonal antibodies (mAbs) have become one of the most important classes of
biopharmaceutical products, and they continue to dominate the universe of …
biopharmaceutical products, and they continue to dominate the universe of …
Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies
Standard cancer therapies sometimes fail to deliver chemotherapeutic drugs to tumor cells
in a safe and effective manner. Nanotechnology takes the lead in providing new therapeutic …
in a safe and effective manner. Nanotechnology takes the lead in providing new therapeutic …
[HTML][HTML] Reprogramming bacteriophage host range: design principles and strategies for engineering receptor binding proteins
Highlights•Phages use structurally diverse receptor binding proteins (RBPs) to target
different cell wall structures.•RBPs play a critical role in spatial and temporal positioning of …
different cell wall structures.•RBPs play a critical role in spatial and temporal positioning of …
[HTML][HTML] Oral inhalation for delivery of proteins and peptides to the lungs
E Fröhlich, S Salar-Behzadi - European Journal of Pharmaceutics and …, 2021 - Elsevier
Oral inhalation is the preferred route for delivery of small molecules to the lungs, because
high tissue levels can be achieved shortly after application. Biologics are mainly …
high tissue levels can be achieved shortly after application. Biologics are mainly …
An overview of antibody conjugated polymeric nanoparticles for breast cancer therapy
Nanoparticles (NPs) are promising drug delivery systems (DDS) for identifying and treating
cancer. Active targeting NPs can be generated by conjugation with ligands that bind …
cancer. Active targeting NPs can be generated by conjugation with ligands that bind …
Antibody conjugates-recent advances and future innovations
Monoclonal antibodies have evolved from research tools to powerful therapeutics in the past
30 years. Clinical success rates of antibodies have exceeded expectations, resulting in …
30 years. Clinical success rates of antibodies have exceeded expectations, resulting in …
Research progress on chemiluminescence immunoassay combined with novel technologies
Q **ao, C Xu - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Chemiluminescence immunoassay (CLIA) has been greatly developed in the past several
decades due to its good sensitivity and specificity. Nowadays, CLIA has been highly …
decades due to its good sensitivity and specificity. Nowadays, CLIA has been highly …
Antibody-mediated drug delivery
FB Arslan, K Ozturk, S Calis - International Journal of Pharmaceutics, 2021 - Elsevier
Passive and active targeted nanoparticulate delivery systems show promise to compensate
for lacking properties of conventional therapy such as side effects, insufficient efficiency and …
for lacking properties of conventional therapy such as side effects, insufficient efficiency and …
HER2-targeted therapies in gastric cancer
Y Zhu, X Zhu, X Wei, C Tang, W Zhang - Biochimica et Biophysica Acta …, 2021 - Elsevier
Molecular targeted therapy of cancer has always been the focus of clinicians. Among those
therapeutic targets, the human epidermal growth factor receptor-2 (HER-2) signaling …
therapeutic targets, the human epidermal growth factor receptor-2 (HER-2) signaling …