Rhabdomyosarcoma

SX Skapek, A Ferrari, AA Gupta, PJ Lupo… - Nature reviews disease …, 2019 - nature.com
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and
represents a high-grade neoplasm of skeletal myoblast-like cells. Decades of clinical and …

Current and future treatment strategies for rhabdomyosarcoma

C Chen, H Dorado Garcia, M Scheer… - Frontiers in …, 2019 - frontiersin.org
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be
subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last …

An update on rhabdomyosarcoma risk stratification and the rationale for current and future Children's Oncology Group clinical trials

JH Haduong, CM Heske… - Pediatric blood & …, 2022 - Wiley Online Library
Children and adolescents with rhabdomyosarcoma (RMS) comprise a heterogeneous
population with variable overall survival rates ranging between approximately 6% and 100 …

Refinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: a report from the …

E Hibbitts, YY Chi, DS Hawkins, FG Barr… - Cancer …, 2019 - Wiley Online Library
Background Previous studies of the prognostic importance of FOXO1 fusion status in
patients with rhabdomyosarcoma (RMS) have had conflicting results. We re‐examined risk …

[HTML][HTML] Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue …

S Hettmer, CM Linardic, A Kelsey, ER Rudzinski… - European Journal of …, 2022 - Elsevier
Rhabdomyosarcomas (RMSs) are the most common soft tissue sarcomas in
children/adolescents less than 18 years of age with an annual incidence of 1–2/million …

MRI of rhabdomyosarcoma and other soft-tissue sarcomas in children

EJ Inarejos Clemente, M Navallas… - Radiographics, 2020 - pubs.rsna.org
Soft-tissue sarcomas in children comprise a heterogeneous group of entities with variable
manifestation depending on the age of the patient and the location of the tumor. MRI is the …

Pathology of childhood rhabdomyosarcoma: a consensus opinion document from the children's oncology group, European paediatric soft tissue sarcoma study group …

ER Rudzinski, A Kelsey, C Vokuhl… - Pediatric blood & …, 2021 - Wiley Online Library
The diagnosis and classification of rhabdomyosarcoma (RMS) has undergone several shifts
over the last 30 years. While the main diagnostic categories remained the same, changes in …

Relapsed rhabdomyosarcoma

CM Heske, L Mascarenhas - Journal of clinical medicine, 2021 - mdpi.com
Relapsed rhabdomyosarcoma (RMS) represents a significant therapeutic challenge. Nearly
one-third of patients diagnosed with localized RMS and over two-thirds of patients with …

Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: a report from the Children's Oncology Group

ER Rudzinski, JR Anderson, YY Chi… - Pediatric blood & …, 2017 - Wiley Online Library
Background Distinguishing alveolar rhabdomyosarcoma (ARMS) from embryonal
rhabdomyosarcoma (ERMS) has historically been of prognostic and therapeutic importance …

Spindle and round cell sarcoma with EWSR1-PATZ1 gene fusion: a sarcoma with polyphenotypic differentiation

A Chougule, MS Taylor, V Nardi, I Chebib… - The American journal …, 2019 - journals.lww.com
The evolving classification of round cell sarcomas is driven by molecular alterations. EWSR1-
PATZ1 fusion positive spindle and round cell sarcoma is one such new tumor entity. Herein …