Many biological activities of pyridine and thiazole derivatives have been reported, including
antiviral activity and, more recently, as COVID-19 inhibitors. Thus, in this paper, we …

Background Thiazole and thiosemicarbazone derivatives are known to have potential
anticancer activity with a mechanism of action related to inhibition of matrix metallo …

The development of new approaches for the synthesis of new bioactive heterocyclic
derivatives is of the utmost importance for pharmaceutical industry. In this regard, the …

A series of new indenoquinoxaline-thiazole hybrids were synthesized by combining
indenoquinoxaline thiosemicarbazone with appropriate hydrazonoyl chlorides or α-halo …

Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological
activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4, 5-dihydro-1 H-pyrazole-1-carbothioamides …

One of the worst diseases, cancer claims millions of lives each year throughout the world,
necessitating the creation of novel treatments. In this study, we designed a novel series of 1 …

A series of novel hydrazinecarbothioamide, 1, 2, 4-triazole-3-thione, 4-thiazolidinone and 1,
3, 4-oxadiazole derivatives were synthesized and evaluated for their cytotoxic activity …

The essential enzyme cyclin-dependent kinase 2 (CDK2) is a promising target for anticancer
drug development due to its pivotal role in regulating the cell cycle. This study aimed to …

The reaction of 2-(1-(2-(2-(4-methoxybenzylidene) hydrazinyl)-4-methylthiazol-5-yl)
ethylidene) hydrazinecarbothioamide with a range of hydrazonoyl chlorides and α-halo …

The reaction of one equivalents of 5‐acetylthiadiazole with one equivalent of aldehyde in
acetic acid and ammonium acetate yielded thiadiazolyl‐pyridine derivatives in a …