Effects of an engineered human anti–TNF-α antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM

F Ofei, S Hurel, J Newkirk, M Sopwith, R Taylor - Diabetes, 1996 - diabetesjournals.org
Inhibition of tumor necrosis factor (TNF)-α action has recently been shown to reverse insulin
resistance dramatically and to improve glycemic control in obese rodents. This double-blind …

[PDF][PDF] Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men

ML Hartman, JD Veldhuis, ML Johnson… - The Journal of …, 1992 - researchgate.net
Serum GH concentrations are increased in fasted or malnourished human subjects. We
investigated the dynamic mechanisms underlying this phenomenon in nine normal men by …

Association between blood lactate and acid-base status and mortality in ventilated babies

SA Deshpande, MPW Platt - Archives of Disease in Childhood-Fetal and …, 1997 - fn.bmj.com
AIM To investigate the relation between common acid-base parameters and blood lactate
concentrations and their prognostic importance in sick, ventilated neonates. METHODS Two …

Selection criteria for human embryo transfer: a comparison of pyruvate uptake and morphology

J Conaghan, K Hardy, AH Handyside… - Journal of assisted …, 1993 - Springer
Purpose Pyruvate uptake is higher in human embryos develo** to the blastocyst stage
than those arresting at cleavage stages. To investigate whether pyruvate uptake provides an …

Acute effects on insulin sensitivity and diurnal metabolic profiles of a high-sucrose compared with a high-starch diet

ME Daly, C Vale, M Walker, A Littlefield… - The American journal of …, 1998 - Elsevier
Decreased insulin sensitivity is associated with diabetes mellitus, ischemic heart disease,
and hypertension, both independently and in association as what is called the metabolic …

The effect of intravenous metformin on glucose metabolism during hyperglycaemia in type 2 diabetes

CF Sum, JM Webster, AB Johnson… - Diabetic …, 1992 - Wiley Online Library
A stepped intravenous metformin infusion was used in conjunction with the hyperglycaemic
clamp technique to study the dose‐response relationship of plasma metformin concentration …

Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure

S Nielsen, N Møller, JS Christiansen… - Diabetes, 2001 - diabetesjournals.org
Stimulation of lipolysis and the induction of resistance to insulin's actions on glucose
metabolism are well-recognized effects of growth hormone (GH). To evaluate whether these …

A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans.

ML Hartman, PE Clayton, ML Johnson, A Celniker… - The Journal of clinical …, 1993 - jci.org
To determine if insulin-like growth factor I (IGF-I) inhibits pulsatile growth hormone (GH)
secretion in man, recombinant human IGF-I (rhIGF-I) was infused for 6 h at 10 micrograms …

The amylin analog pramlintide improves glycemic control and reduces postprandial glucagon concentrations in patients with type 1 diabetes mellitus

B Nyholm, L Ørskov, KY Hove, CH Gravholt, N Møller… - Metabolism, 1999 - Elsevier
To explore further the effects of the human amylin analog pramlintide on overall glycemic
control and postprandial responses of circulating glucose, glucagon, and metabolic …

Glucose and lactate concentration determination on single microsamples by Fourier-transform infrared spectroscopy

C Petibois, AM Melin, A Perromat, G Cazorla… - Journal of Laboratory …, 2000 - Elsevier
This study is the first to assess the analytic potential of Fourier-transform infrared (FT-IR)
spectroscopy in determining exercise-induced metabolic changes, such as glucose and …