Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
[HTML][HTML] Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming
Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …
since their discovery. However, their use in therapy has been complicated by severe side …
Enhanced Immunogenic Cell Death and Antigen Presentation via Engineered Bifidobacterium bifidum to Boost Chemo-immunotherapy
T He, L Wang, S Gou, L Lu, G Liu, K Wang, Y Yang… - ACS …, 2023 - ACS Publications
The immunogenic cell death (ICD) of tumor cells has aroused great interest in the field of
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …
immunotherapy, mainly due to the production of plentiful tumor-associated antigens (TAAs) …
Mitochondria and doxorubicin-induced cardiomyopathy: a complex interplay
Cardiotoxicity has emerged as a major side effect of doxorubicin (DOX) treatment, affecting
nearly 30% of patients within 5 years after chemotherapy. Heart failure is the first non-cancer …
nearly 30% of patients within 5 years after chemotherapy. Heart failure is the first non-cancer …
Milk/colostrum exosomes: A nanoplatform advancing delivery of cancer therapeutics
Chemotherapeutics continue to play a central role in the treatment of a wide variety of
cancers. Conventional chemotherapy involving bolus intravenous doses results in severe …
cancers. Conventional chemotherapy involving bolus intravenous doses results in severe …
Designing covalent organic framework‐based light‐driven microswimmers toward therapeutic applications
While micromachines with tailored functionalities enable therapeutic applications in
biological environments, their controlled motion and targeted drug delivery in biological …
biological environments, their controlled motion and targeted drug delivery in biological …
Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery
Microneedles (MNs) have recently been found to have applications in drug, vitamin, protein
and vaccine delivery. Polymeric MN arrays continue to attract increasing attention due to …
and vaccine delivery. Polymeric MN arrays continue to attract increasing attention due to …
Micelle-engineered nanoplatforms for precision oncology
The alliance between nanomaterials and cancer therapy has revolutionized the treatment of
tumor patients. After cardiovascular diseases, cancer is the leading cause of death, so …
tumor patients. After cardiovascular diseases, cancer is the leading cause of death, so …
[HTML][HTML] Bioactive compound encapsulation: Characteristics, applications in food systems, and implications for human health
A Rezagholizade-Shirvan, M Soltani, S Shokri… - Food chemistry: X, 2024 - Elsevier
Nanotechnology plays a pivotal role in food science, particularly in the nanoencapsulation of
bioactive compounds, to enhance their stability, bioavailability, and therapeutic potential …
bioactive compounds, to enhance their stability, bioavailability, and therapeutic potential …
Environmental implications of metal–organic frameworks and MXenes in biomedical applications: a perspective
Metal–organic frameworks (MOFs) and MXenes have demonstrated immense potential for
biomedical applications, offering a plethora of advantages. MXenes, in particular, exhibit …
biomedical applications, offering a plethora of advantages. MXenes, in particular, exhibit …