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Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Subcortical brain structures are involved in developmental, psychiatric and neurological
disorders. Here we performed genome-wide association studies meta-analyses of …
disorders. Here we performed genome-wide association studies meta-analyses of …
Shared molecular genetic factors influence subcortical brain morphometry and Parkinson's disease risk
Parkinson's disease (PD) is a late-onset and genetically complex neurodegenerative
disorder. Here we sought to identify genes and molecular pathways underlying the …
disorder. Here we sought to identify genes and molecular pathways underlying the …
Shared genetics and bidirectional causal relationships between type 2 diabetes and attention-deficit/hyperactivity disorder
Background Type 2 diabetes (T2D) is a chronic metabolic disorder with high comorbidity
with mental disorders. The genetic links between attention-deficit/hyperactivity disorder …
with mental disorders. The genetic links between attention-deficit/hyperactivity disorder …
Discontinuation of antidepressant treatment: a retrospective cohort study on more than 20,000 participants
Background Factors influencing antidepressant treatment discontinuation are poorly
understood. In the present study, we aimed to estimate the prevalence of antidepressant …
understood. In the present study, we aimed to estimate the prevalence of antidepressant …
Investigating the shared genetic etiology between Parkinson's disease and depression
P Reyes-Pérez, LM García-Marín… - Journal of …, 2024 - journals.sagepub.com
Background: Depression is a common symptom in Parkinson's disease (PD), resulting from
underlying neuropathological processes and psychological factors. However, the extent to …
underlying neuropathological processes and psychological factors. However, the extent to …
Phenome-wide screening of the putative causal determinants of depression using genetic data
Depression is one of the most common mental health disorders and one of the top causes of
disability throughout the world. The present study sought to identify putative causal …
disability throughout the world. The present study sought to identify putative causal …
Associations between attention-deficit hyperactivity disorder genetic liability and ICD-10 medical conditions in adults: utilizing electronic health records in a Phenome …
BackgroundAttention-deficit hyperactivity disorder (ADHD) is often comorbid with other
medical conditions in adult patients. However, ADHD is extremely underdiagnosed in adults …
medical conditions in adult patients. However, ADHD is extremely underdiagnosed in adults …
[HTML][HTML] Causal relationship between ADHD and frozen shoulder: Two-sample Mendelian randomization
GH Deng - Medicine, 2023 - journals.lww.com
To investigate the causal relationship between attention deficit and hyperactivity disorder
(ADHD) and frozen shoulder using Mendelian randomization (MR). Data were pooled from …
(ADHD) and frozen shoulder using Mendelian randomization (MR). Data were pooled from …
Prevalence of somatic diseases in adults with attention deficit hyperactivity disorder in Japan is highest in people aged≥ 40 years with mental disorders: a cross …
Y Takaesu, Y Sato, S Iwata, P Takizawa… - Frontiers in …, 2024 - frontiersin.org
Introduction Studies have reported an association between attention deficit hyperactivity
disorder (ADHD) and somatic diseases; however, the correlation of mental disorders with …
disorder (ADHD) and somatic diseases; however, the correlation of mental disorders with …
[PDF][PDF] Decoding Causal Associations Between Neuropsychiatric Disorders and Rotator Cuff Tendinopathy: A Two-Sample Mendelian Randomization Study
W Zhang, M Chen, H Huang, P Sheng - 2025 - preprints.org
Background/Objectives: Rotator cuff tendinopathy (RCT) contributes to over 30 million sports-
related surgeries worldwide annually, as a leading cause of shoulder pain and dysfunction …
related surgeries worldwide annually, as a leading cause of shoulder pain and dysfunction …