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Schizophrenia, neuroimaging and connectomics
Schizophrenia is frequently characterized as a disorder of brain connectivity. Neuroimaging
has played a central role in supporting this view, with nearly two decades of research …
has played a central role in supporting this view, with nearly two decades of research …
Diffusion tensor imaging for understanding brain development in early life
The human brain rapidly develops during the final weeks of gestation and in the first two
years following birth. Diffusion tensor imaging (DTI) is a unique in vivo imaging technique …
years following birth. Diffusion tensor imaging (DTI) is a unique in vivo imaging technique …
Is the magnetization transfer ratio a marker for myelin in multiple sclerosis?
Purpose To investigate the correlation between water content (WC) and magnetization
transfer ratio (MTR) in normal and multiple sclerosis (MS) brain. The MTR has been …
transfer ratio (MTR) in normal and multiple sclerosis (MS) brain. The MTR has been …
Achievements and obstacles of remyelinating therapies in multiple sclerosis
Remyelination in the CNS is the natural process of damage repair in demyelinating
diseases such as multiple sclerosis (MS). However, remyelination becomes inadequate in …
diseases such as multiple sclerosis (MS). However, remyelination becomes inadequate in …
Imaging outcomes for trials of remyelination in multiple sclerosis
S Mallik, RS Samson… - Journal of Neurology …, 2014 - jnnp.bmj.com
Trials of potential neuroreparative agents are becoming more important in the spectrum of
multiple sclerosis research. Appropriate imaging outcomes are required that are feasible …
multiple sclerosis research. Appropriate imaging outcomes are required that are feasible …
Imaging outcome measures of neuroprotection and repair in MS: a consensus statement from NAIMS
Objective To summarize current and emerging imaging techniques that can be used to
assess neuroprotection and repair in multiple sclerosis (MS), and to provide a consensus …
assess neuroprotection and repair in multiple sclerosis (MS), and to provide a consensus …
Fast whole-brain three-dimensional macromolecular proton fraction map** in multiple sclerosis
Purpose To evaluate the clinical utility of fast whole-brain macromolecular proton fraction
(MPF macromolecular proton fraction) map** in multiple sclerosis (MS multiple sclerosis) …
(MPF macromolecular proton fraction) map** in multiple sclerosis (MS multiple sclerosis) …
Quantitative magnetization transfer imaging in relapsing-remitting multiple sclerosis: A systematic review and meta-analysis
Myelin-sensitive MRI such as magnetization transfer imaging has been widely used in
multiple sclerosis. The influence of methodology and differences in disease subtype on …
multiple sclerosis. The influence of methodology and differences in disease subtype on …
Remyelination therapy in multiple sclerosis
DE Harlow, JM Honce, AA Miravalle - Frontiers in neurology, 2015 - frontiersin.org
Multiple sclerosis (MS) is an immune-mediated disorder of the central nervous system that
results in destruction of the myelin sheath that surrounds axons and eventual …
results in destruction of the myelin sheath that surrounds axons and eventual …
Macromolecular proton fraction as a myelin biomarker: principles, validation, and applications
Macromolecular proton fraction (MPF) is a quantitative MRI parameter describing the
magnetization transfer (MT) effect and defined as a relative amount of protons bound to …
magnetization transfer (MT) effect and defined as a relative amount of protons bound to …