Schizophrenia, neuroimaging and connectomics

A Fornito, A Zalesky, C Pantelis, ET Bullmore - Neuroimage, 2012 - Elsevier
Schizophrenia is frequently characterized as a disorder of brain connectivity. Neuroimaging
has played a central role in supporting this view, with nearly two decades of research …

Diffusion tensor imaging for understanding brain development in early life

A Qiu, S Mori, MI Miller - Annual review of psychology, 2015 - annualreviews.org
The human brain rapidly develops during the final weeks of gestation and in the first two
years following birth. Diffusion tensor imaging (DTI) is a unique in vivo imaging technique …

Is the magnetization transfer ratio a marker for myelin in multiple sclerosis?

IM Vavasour, C Laule, DKB Li… - Journal of Magnetic …, 2011 - Wiley Online Library
Purpose To investigate the correlation between water content (WC) and magnetization
transfer ratio (MTR) in normal and multiple sclerosis (MS) brain. The MTR has been …

Achievements and obstacles of remyelinating therapies in multiple sclerosis

M Stangel, T Kuhlmann, PM Matthews… - Nature Reviews …, 2017 - nature.com
Remyelination in the CNS is the natural process of damage repair in demyelinating
diseases such as multiple sclerosis (MS). However, remyelination becomes inadequate in …

Imaging outcomes for trials of remyelination in multiple sclerosis

S Mallik, RS Samson… - Journal of Neurology …, 2014 - jnnp.bmj.com
Trials of potential neuroreparative agents are becoming more important in the spectrum of
multiple sclerosis research. Appropriate imaging outcomes are required that are feasible …

Imaging outcome measures of neuroprotection and repair in MS: a consensus statement from NAIMS

J Oh, D Ontaneda, C Azevedo, EC Klawiter, M Absinta… - Neurology, 2019 - neurology.org
Objective To summarize current and emerging imaging techniques that can be used to
assess neuroprotection and repair in multiple sclerosis (MS), and to provide a consensus …

Fast whole-brain three-dimensional macromolecular proton fraction map** in multiple sclerosis

VL Yarnykh, JD Bowen, A Samsonov, P Repovic… - Radiology, 2015 - pubs.rsna.org
Purpose To evaluate the clinical utility of fast whole-brain macromolecular proton fraction
(MPF macromolecular proton fraction) map** in multiple sclerosis (MS multiple sclerosis) …

Quantitative magnetization transfer imaging in relapsing-remitting multiple sclerosis: A systematic review and meta-analysis

EN York, MJ Thrippleton, R Meijboom… - Brain …, 2022 - academic.oup.com
Myelin-sensitive MRI such as magnetization transfer imaging has been widely used in
multiple sclerosis. The influence of methodology and differences in disease subtype on …

Remyelination therapy in multiple sclerosis

DE Harlow, JM Honce, AA Miravalle - Frontiers in neurology, 2015 - frontiersin.org
Multiple sclerosis (MS) is an immune-mediated disorder of the central nervous system that
results in destruction of the myelin sheath that surrounds axons and eventual …

Macromolecular proton fraction as a myelin biomarker: principles, validation, and applications

AA Kisel, AV Naumova, VL Yarnykh - Frontiers in neuroscience, 2022 - frontiersin.org
Macromolecular proton fraction (MPF) is a quantitative MRI parameter describing the
magnetization transfer (MT) effect and defined as a relative amount of protons bound to …