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Dysfunction of mesenchymal stem cells isolated from metabolic syndrome and type 2 diabetic patients as result of oxidative stress and autophagy may limit their …
K Kornicka, J Houston, K Marycz - Stem cell reviews and reports, 2018 - Springer
Mesenchymal stem cells (MSC) have become a promising tool for therapeutic intervention.
Their unique features, including self-renewal, multipotency and immunomodulatory …
Their unique features, including self-renewal, multipotency and immunomodulatory …
Wharton's jelly derived mesenchymal stem cells: future of regenerative medicine? Recent findings and clinical significance
I Kalaszczynska, K Ferdyn - BioMed research international, 2015 - Wiley Online Library
Around 5 million annual births in EU and 131 million worldwide give a unique opportunity to
collect lifesaving Wharton's jelly derived mesenchymal stem cells (WJ‐MSC). Evidences that …
collect lifesaving Wharton's jelly derived mesenchymal stem cells (WJ‐MSC). Evidences that …
Stem cell therapy to cure type 1 diabetes: from hype to hope
Type 1 diabetes mellitus (T1D) is a chronic, multifactorial autoimmune disease that involves
the progressive destruction of pancreatic β-cells, ultimately resulting in the loss of insulin …
the progressive destruction of pancreatic β-cells, ultimately resulting in the loss of insulin …
Type 2 diabetes mellitus duration and obesity alter the efficacy of autologously transplanted bone marrow-derived mesenchymal stem/stromal cells
Human bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) represent
promising stem cell therapy for the treatment of type 2 diabetes mellitus (T2DM), but the …
promising stem cell therapy for the treatment of type 2 diabetes mellitus (T2DM), but the …
The effect of chronic inflammation and oxidative and endoplasmic reticulum stress in the course of metabolic syndrome and its therapy
M Alicka, K Marycz - Stem Cells International, 2018 - Wiley Online Library
Metabolic syndrome (MetS) is highly associated with a modern lifestyle. The prevalence of
MetS has reached epidemic proportion and is still rising. The main cause of MetS and finally …
MetS has reached epidemic proportion and is still rising. The main cause of MetS and finally …
[HTML][HTML] Impact of type 2 diabetes mellitus on human bone marrow stromal cell number and phenotypic characteristics
Human bone marrow-derived mesenchymal stromal cells (MSCs) have been investigated in
numerous disease settings involving impaired regeneration because of the crucial role they …
numerous disease settings involving impaired regeneration because of the crucial role they …
Concise review: mesenchymal stem cells for diabetes
Mesenchymal stem cells (MSCs) have already made their mark in the young field of
regenerative medicine. Easily derived from many adult tissues, their therapeutic worth has …
regenerative medicine. Easily derived from many adult tissues, their therapeutic worth has …
Making surrogate β-cells from mesenchymal stromal cells: perspectives and future endeavors
Generation of surrogate β-cells is the need of the day to compensate the short supply of
islets for transplantation to diabetic patients requiring daily shots of insulin. Over the years …
islets for transplantation to diabetic patients requiring daily shots of insulin. Over the years …
Human bone marrow-derived mesenchymal cells differentiate and mature into endocrine pancreatic lineage in vivo
SM Phadnis, MV Joglekar, MP Dalvi, S Muthyala… - …, 2011 - Taylor & Francis
Background aims. The scarcity of human islets for transplantation remains a major limitation
of cell replacement therapy for diabetes. Bone marrow-derived progenitor cells are of …
of cell replacement therapy for diabetes. Bone marrow-derived progenitor cells are of …
High glucose-induced reactive oxygen species generation promotes stemness in human adipose-derived stem cells
Background aims Adipose-derived stem cells (ASCs) represent an important source of cell
therapy to treat diabetic complications. However, hyperglycemia may alter several cellular …
therapy to treat diabetic complications. However, hyperglycemia may alter several cellular …