Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

Dyslipidemia is an important risk factor for coronary artery disease and stroke. All persons
with dyslipidemia should be advised to focus on lifestyle interventions, including regular …

Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …

Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart
Association | Circulation Skip to main content Become a member Volunteer Donate centennial Go …

Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

Abstract Historically, low-carbohydrate (CHO) and very-low-CHO diets have been used for
weight loss. Recently, these diets have been promoted for type 2 diabetes (T2D) …

Antisense oligonucleotides (ASOs) bind sequence specifically to the target RNA and
modulate protein expression through several different mechanisms. The ASO field is an …

Dyslipidemia is the risk of cardiovascular disease, and their relationship is clear. Lowering
serum cholesterol can reduce the risk of coronary heart disease. At present, the main …

It is now about 20 years since the first case of a gain-of-function mutation involving the as-yet-
unknown actor in cholesterol homeostasis, proprotein convertase subtilisin/kexin type 9 …

Abstract Background: Approximately 7% of American adults have severe
hypercholesterolemia (untreated low-density lipoprotein [LDL] cholesterol≥ 190 mg/dl) …