[HTML][HTML] Long non-coding RNA in the pathogenesis of cancers

Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Regulation and function of SOX9 during cartilage development and regeneration

H Song, KH Park - Seminars in cancer biology, 2020 - Elsevier
Chondrogenesis is a highly coordinated event in embryo development, adult homeostasis,
and repair of the vertebrate cartilage. Fate decisions and differentiation of chondrocytes …

Long noncoding RNA FAM225A promotes nasopharyngeal carcinoma tumorigenesis and metastasis by acting as ceRNA to sponge miR-590-3p/miR-1275 and …

ZQ Zheng, ZX Li, GQ Zhou, L Lin, LL Zhang… - Cancer …, 2019 - aacrjournals.org
Long noncoding RNAs (lncRNA) play important roles in the tumorigenesis and progression
of cancers. However, the clinical significance of lncRNAs and their regulatory mechanisms …

Neuroblastoma—a neural crest derived embryonal malignancy

JI Johnsen, C Dyberg, M Wickström - Frontiers in molecular …, 2019 - frontiersin.org
Neuroblastoma is a neural crest derived malignancy of the peripheral nervous system and is
the most common and deadliest tumor of infancy. It is characterized by clinical heterogeneity …

[HTML][HTML] Emerging roles of lncRNAs in the post-transcriptional regulation in cancer

RZ He, DX Luo, YY Mo - Genes & diseases, 2019 - Elsevier
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) can play a pivotal
role in regulation of diverse cellular processes. In particular, lncRNAs can serve as master …

The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

L Wei, X Wang, L Lv, J Liu, H **ng, Y Song, M **e… - Molecular Cancer, 2019 - Springer
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the
second most lethal human cancer. A portion of patients with advanced HCC can significantly …

FOXC1-mediated LINC00301 facilitates tumor progression and triggers an immune-suppressing microenvironment in non-small cell lung cancer by regulating the …

CC Sun, W Zhu, SJ Li, W Hu, J Zhang, Y Zhuo… - Genome medicine, 2020 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are extensively intricate in the
tumorigenesis and metastasis of various cancer types. Nevertheless, the detailed molecular …

Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance

L Yuan, ZY Xu, SM Ruan, S Mo, JJ Qin, XD Cheng - Molecular cancer, 2020 - Springer
Gastric cancer is a deadly disease and remains the third leading cause of cancer-related
death worldwide. The 5-year overall survival rate of patients with early-stage localized …

Deubiquitylating enzymes in cancer and immunity

J Ren, P Yu, S Liu, R Li, X Niu, Y Chen… - Advanced …, 2023 - Wiley Online Library
Deubiquitylating enzymes (DUBs) maintain relative homeostasis of the cellular ubiquitome
by removing the post‐translational modification ubiquitin moiety from substrates. Numerous …

LncRNA HAND2‐AS1 promotes liver cancer stem cell self‐renewal via BMP signaling

Y Wang, P Zhu, J Luo, J Wang, Z Liu, W Wu… - The EMBO …, 2019 - embopress.org
Hepatocellular carcinoma (HCC) is the most prevalent liver cancer, characterized by a high
rate of recurrence and heterogeneity. Liver cancer stem cells (CSCs) may well contribute to …