Green metrics in mechanochemistry

N Fantozzi, JN Volle, A Porcheddu, D Virieux… - Chemical Society …, 2023 - pubs.rsc.org
The development of new green methodologies and their broader adoption for promoting
sustainable development in chemistry laboratories and industry play a significant role in …

Mechanochemistry: new tools to navigate the uncharted territory of “impossible” reactions

F Cuccu, L De Luca, F Delogu, E Colacino… - …, 2022 - Wiley Online Library
Mechanochemical transformations have made chemists enter unknown territories, forcing a
different chemistry perspective. While questioning or revisiting familiar concepts belonging …

Sustainability assessment of mechanochemistry by using the twelve principles of green chemistry

KJ Ardila‐Fierro, JG Hernández - ChemSusChem, 2021 - Wiley Online Library
In recent years, mechanochemistry has been growing into a widely accepted alternative for
chemical synthesis. In addition to their efficiency and practicality, mechanochemical …

Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis

RRA Bolt, JA Leitch, AC Jones, WI Nicholson… - Chemical Society …, 2022 - pubs.rsc.org
Rapid and wide-ranging developments have established mechanochemistry as a powerful
avenue in sustainable organic synthesis. This is primarily due to unique opportunities which …

Liquid‐assisted grinding mechanochemistry in the synthesis of pharmaceuticals

P Ying, J Yu, W Su - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
Mechanochemical reactions by milling, grinding or other types of mechanical action have
emerged as a salient green approach because of its wide applications towards academic …

Tribochemistry, mechanical alloying, mechanochemistry: what is in a name?

AAL Michalchuk, EV Boldyreva, AM Belenguer… - Frontiers in …, 2021 - frontiersin.org
Over the decades, the application of mechanical force to influence chemical reactions has
been called by various names: mechanochemistry, tribochemistry, mechanical alloying, to …

Tinkering with mechanochemical tools for scale up

JF Reynes, V Isoni, F García - … Chemie International Edition, 2023 - Wiley Online Library
Mechanochemistry provides an environmentally benign platform to develop more
sustainable chemical processes by limiting raw materials, energy use, and waste generation …

Mechanochemistry can reduce life cycle environmental impacts of manufacturing active pharmaceutical ingredients

O Galant, G Cerfeda, AS McCalmont… - ACS Sustainable …, 2022 - ACS Publications
The scale-up of mechanochemical methods could play a transformative role in making
manufacturing processes in the pharmaceutical industry greener by eliminating solvent use …

Salient achievements in synthetic organic chemistry enabled by mechanochemical activation

E Juaristi, CG Avila-Ortiz - Synthesis, 2023 - thieme-connect.com
Although known for millennia, it is only recently that mechanochemistry has received serious
attention by chemists. Indeed, during the past 15 years an extraordinary number of reports …

Catalyst-free mechanochemistry as a versatile tool in synthetic chemistry: a review

BR Naidu, T Sruthi, R Mitty, K Venkateswarlu - Green Chemistry, 2023 - pubs.rsc.org
A notable advancement of the mechanochemical process has been its ability to initiate
reactions that are otherwise extremely difficult/impossible to accomplish. For the first time, in …