Fertile ground: human endometrial programming and lessons in health and disease
The human endometrium is a highly dynamic tissue that is cyclically shed, repaired,
regenerated and remodelled, primarily under the orchestration of oestrogen and …
regenerated and remodelled, primarily under the orchestration of oestrogen and …
Role of vascular endothelial growth factor (VEGF) in human embryo implantation: clinical implications
X Guo, H Yi, TC Li, Y Wang, H Wang, X Chen - Biomolecules, 2021 - mdpi.com
Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that plays a
critical role in various physiological and pathological processes. VEGF also contributes to …
critical role in various physiological and pathological processes. VEGF also contributes to …
VEGF may contribute to macrophage recruitment and M2 polarization in the decidua
It is increasingly evident that cytokines and growth factors produced in the decidua play a
pivotal role in the regulation of the local immune microenvironment and the establishment of …
pivotal role in the regulation of the local immune microenvironment and the establishment of …
Endometrial exosomes/microvesicles in the uterine microenvironment: a new paradigm for embryo-endometrial cross talk at implantation
YH Ng, S Rome, A Jalabert, A Forterre, H Singh… - PloS one, 2013 - journals.plos.org
Exosomes are nanoparticles (∼ 100 nm diameter) released from cells, which can transfer
small RNAs and mRNA via the extracellular environment to cells at distant sites. We …
small RNAs and mRNA via the extracellular environment to cells at distant sites. We …
The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction
BACKGROUND Although laboratory procedures, along with culture media formulations,
have improved over the past two decades, the issue remains that human IVF is performed in …
have improved over the past two decades, the issue remains that human IVF is performed in …
Molecular signaling regulating endometrium–blastocyst crosstalk
M Massimiani, V Lacconi, F La Civita, C Ticconi… - International journal of …, 2019 - mdpi.com
Implantation of the embryo into the uterine endometrium is one of the most finely-regulated
processes that leads to the establishment of a successful pregnancy. A plethora of factors …
processes that leads to the establishment of a successful pregnancy. A plethora of factors …
Human endometrial exosomes contain hormone-specific cargo modulating trophoblast adhesive capacity: insights into endometrial-embryo interactions
DW Greening, HPT Nguyen, K Elgass… - Biology of …, 2016 - academic.oup.com
Embryo implantation into receptive endometrium requires synergistic endometrial-blastocyst
interactions within the uterine cavity and is essential for establishing pregnancy. We …
interactions within the uterine cavity and is essential for establishing pregnancy. We …
Uterine glands: developmental biology and functional roles in pregnancy
All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
The vascular endothelial growth factor family in adverse pregnancy outcomes
BACKGROUND Pre-eclampsia, small-for-gestational-age infants, preterm birth and
recurrent miscarriage complicate a significant number of pregnancies. The vascular …
recurrent miscarriage complicate a significant number of pregnancies. The vascular …
Single-cell insights into epithelial morphogenesis in the neonatal mouse uterus
TE Spencer, MT Lowke… - Proceedings of the …, 2023 - National Acad Sciences
The uterus is vital for successful reproduction in mammals, and two different types of
epithelia (luminal and glandular) are essential for embryo implantation and pregnancy …
epithelia (luminal and glandular) are essential for embryo implantation and pregnancy …