Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds
HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
Targeting autophagy using natural compounds for cancer prevention and therapy
S Deng, MK Shanmugam, AP Kumar, CT Yap, G Sethi… - Cancer, 2019 - Wiley Online Library
Autophagy, also known as macroautophagy, is a tightly regulated process involved in the
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
stress responses, such as starvation. It is a vacuolar, lysosomal pathway for the degradation …
Thymoquinone and its therapeutic potentials
S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …
alternatives to chemical drugs. Several lines of evidence support the positive impact of …
Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review
Z Gholamnezhad, S Havakhah… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Nigella sativa (N. sativa) L.(Ranunculaceae), well known
as black cumin, has been used as a herbal medicine that has a rich historical background. It …
as black cumin, has been used as a herbal medicine that has a rich historical background. It …
Black cumin (Nigella sativa) and its active constituent, thymoquinone: an overview on the analgesic and anti-inflammatory effects
B Amin, H Hosseinzadeh - Planta medica, 2016 - thieme-connect.com
For many centuries, seeds of Nigella sativa (black cumin), a dicotyledon of the
Ranunculaceae family, have been used as a seasoning spice and food additive in the …
Ranunculaceae family, have been used as a seasoning spice and food additive in the …
Targeting transcription factor STAT3 for cancer prevention and therapy
EZP Chai, MK Shanmugam, F Arfuso… - Pharmacology & …, 2016 - Elsevier
Abstract Signal Transducers and Activators of Transcription (STATs) comprise an important
class of transcription factors that have been implicated in a wide variety of essential cellular …
class of transcription factors that have been implicated in a wide variety of essential cellular …
Immunomodulatory and anti-inflammatory action of Nigella sativa and thymoquinone: A comprehensive review
Many herbal products are now used as remedies to treat various infectious and non-
infectious conditions. Even though the use of herbs and natural products is much more …
infectious conditions. Even though the use of herbs and natural products is much more …
[HTML][HTML] Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects
Cancer remains the topmost disorder of the mankind and number of cases is unceasingly
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …
[HTML][HTML] Thymoquinone: an emerging natural drug with a wide range of medical applications
Nigella sativa has attracted healers in ancient civilizations and researchers in recent times.
Traditionally, it has been used in different forms to treat many diseases including asthma …
Traditionally, it has been used in different forms to treat many diseases including asthma …
Potential role of natural compounds as anti-angiogenic agents in cancer
MK Shanmugam, S Warrier, AP Kumar… - Current vascular …, 2017 - ingentaconnect.com
Background: Neovascularization, also known as angiogenesis, is the process of capillary
sprouting from pre-existing blood vessels. This physiological process is a hallmark event in …
sprouting from pre-existing blood vessels. This physiological process is a hallmark event in …