Multi-omics data integration, interpretation, and its application
I Subramanian, S Verma, S Kumar… - … and biology insights, 2020 - journals.sagepub.com
To study complex biological processes holistically, it is imperative to take an integrative
approach that combines multi-omics data to highlight the interrelationships of the involved …
approach that combines multi-omics data to highlight the interrelationships of the involved …
Tumor heterogeneity in breast cancer
G Turashvili, E Brogi - Frontiers in medicine, 2017 - frontiersin.org
Breast cancer is a heterogeneous disease and differs greatly among different patients
(intertumor heterogeneity) and even within each individual tumor (intratumor heterogeneity) …
(intertumor heterogeneity) and even within each individual tumor (intratumor heterogeneity) …
The chromatin accessibility landscape of primary human cancers
INTRODUCTION Cancer is one of the leading causes of death worldwide. Although the 2%
of the human genome that encodes proteins has been extensively studied, much remains to …
of the human genome that encodes proteins has been extensively studied, much remains to …
Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
Single-cell transcriptome profiling of tumour tissue isolates allows the characterization of
heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we …
heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we …
Molecular subtypes and local-regional control of breast cancer
SM Fragomeni, A Sciallis… - Surgical Oncology …, 2018 - surgonc.theclinics.com
Breast cancer is a heterogeneous disease that affects one anatomic site, yet is
phenotypically variable. 1, 2 The identification of different biological subtypes occurs …
phenotypically variable. 1, 2 The identification of different biological subtypes occurs …
[HTML][HTML] Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast …
ABSTRACT The 14th St Gallen International Breast Cancer Conference (2015) reviewed
substantial new evidence on locoregional and systemic therapies for early breast cancer …
substantial new evidence on locoregional and systemic therapies for early breast cancer …
[HTML][HTML] Biological subtypes of breast cancer: Prognostic and therapeutic implications
O Yersal, S Barutca - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
Breast cancer is a heterogeneous complex of diseases, a spectrum of many subtypes with
distinct biological features that lead to differences in response patterns to various treatment …
distinct biological features that lead to differences in response patterns to various treatment …
[HTML][HTML] Cancer hallmarks, biomarkers and breast cancer molecular subtypes
X Dai, L **ang, T Li, Z Bai - Journal of cancer, 2016 - ncbi.nlm.nih.gov
Breast cancer is a complex disease encompassing multiple tumor entities, each
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …
[HTML][HTML] Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early …
A Goldhirsch, EP Winer, AS Coates, RD Gelber… - Annals of oncology, 2013 - Elsevier
Abstract The 13th St Gallen International Breast Cancer Conference (2013) Expert Panel
reviewed and endorsed substantial new evidence on aspects of the local and regional …
reviewed and endorsed substantial new evidence on aspects of the local and regional …
Comparison of the performance of 6 prognostic signatures for estrogen receptor–positive breast cancer: a secondary analysis of a randomized clinical trial
Importance Multiple molecular signatures are available for managing estrogen receptor (ER)–
positive breast cancer but with little direct comparative information to guide the patient's …
positive breast cancer but with little direct comparative information to guide the patient's …