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Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects
S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …
fluorescent markers or for the detection of biomolecules owing to their good optical physical …
Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …
The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy
Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …
Efficient NIR-II type-I AIE photosensitizer for mitochondria-targeted photodynamic therapy through synergistic apoptosis–ferroptosis
J Zhuang, B Wang, H Chen, K Zhang, N Li, N Zhao… - ACS …, 2023 - ACS Publications
Hypoxia, the hallmark of malignant tumors, has been recognized as a major obstacle for
photodynamic therapy (PDT). Precisely targeting cancer cells in intricate biological …
photodynamic therapy (PDT). Precisely targeting cancer cells in intricate biological …
An ER‐targeted, viscosity‐sensitive hemicyanine dye for the diagnosis of nonalcoholic fatty liver and photodynamic cancer therapy by activating pyroptosis pathway
S Zeng, Y Wang, C Chen, H Kim, X Liu… - Angewandte Chemie …, 2024 - Wiley Online Library
The concept of molecular design, integrating diagnostic and therapeutic functions, aligns
with the general trend of modern medical advancement. Herein, we rationally designed the …
with the general trend of modern medical advancement. Herein, we rationally designed the …
Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Tumor-generated reactive oxygen species storm for high-performance ferroptosis therapy
L Huang, J Zhu, W ** engineering to modulate lattice and electronic structure for enhanced piezocatalytic therapy and ferroptosis
B Tian, R Tian, S Liu, Y Wang, S Gai, Y **e… - Advanced …, 2023 - Wiley Online Library
Piezocatalytic therapy, which generates reactive oxygen species (ROS) under mechanical
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …
Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …