Brain-specific targeted delivery of therapeutic agents using metal–organic framework-based nanomedicine

Z Han, M Yuan, N Nguyen, HC Zhou… - Coordination Chemistry …, 2024 - Elsevier
Brain-targeting drug delivery remains a massive challenge due to the complexity and
delicacy of the human brain. However, it is of paramount importance because many …

Emerging trends in bilosomes as therapeutic drug delivery systems

H Kaurav, M Tripathi, SD Kaur, A Bansal, DN Kapoor… - Pharmaceutics, 2024 - mdpi.com
Background: Open Access Editor's Choice Review Emerging Trends in Bilosomes as
Therapeutic Drug Delivery Systems by Hemlata Kaurav 1, Meenakshi Tripathi 1, Simran …

Fabrication of betaxolol hydrochloride-loaded highly permeable ocular bilosomes (HPOBs) to combat glaucoma: In vitro, ex vivo & in vivo characterizations

MG Sakr, SA El-Zahaby, AM Al-Mahallawi… - Journal of Drug Delivery …, 2023 - Elsevier
Betaxolol hydrochloride is a water-soluble antiglaucoma drug suffering from poor ocular
bioavailability necessitating frequent dosing that impede patient adherence to treatment …

Development of surface modified bilosomes for the oral delivery of quercetin: Optimization, characterization in-vitro antioxidant, antimicrobial, and cytotoxicity study

NK Alruwaili, A Zafar, OA Alsaidan, M Yasir… - Drug Delivery, 2022 - Taylor & Francis
Quercetin (QT) is a flavonoid that exhibits anti-oxidant and chemo-preventive activity. This
research work aimed to develop surface-modified bilosomes (BS) of QT. The BS was …

Bile salt stabilized nanovesicles as a promising drug delivery technology: A general overview and future perspectives

R Abdel-moneum, RS Abdel-Rashid - Journal of drug delivery science and …, 2023 - Elsevier
Bile salts stabilized nanovesicles (bilosomes) have received tremendous attention in the
previous decade due to their vast preferabilities as well as the flexibility of their modification …

Therapeutic potential of cationic bilosomes in the treatment of carrageenan-induced rat arthritis via fluticasone propionate gel

AH AbuBakr, HAFM Hassan, A Abdalla… - International journal of …, 2023 - Elsevier
Arthritis is a debilitating disease that affects the patient's mobility and quality of life. This
study focused on the development and optimization of a cationic nanosized bilosomal …

Unlocking the potential of bilosomes and modified bilosomes: a comprehensive journey into advanced drug delivery trends

D Nayak, M Rathnanand, VK Tippavajhala - AAPS PharmSciTech, 2023 - Springer
Vesicular drug delivery systems have revolutionized the pharmaceutical field, offering a
promising path for achieving targeted and sustained drug delivery. The oral, transdermal …

[HTML][HTML] Novel bile salt stabilized vesicles-mediated effective topical delivery of diclofenac sodium: A new therapeutic approach for pain and inflammation

TM Mahmoud, MM Nafady, HO Farouk, DM Mahmoud… - Pharmaceuticals, 2022 - mdpi.com
The oral delivery of diclofenac sodium (DNa), a non-steroidal analgesic, anti-inflammatory
drug, is associated with various gastrointestinal side effects. The aim of the research was to …

Hyaluronic Acid‐Coated Chitosan/Gelatin Nanoparticles as a New Strategy for Topical Delivery of Metformin in Melanoma

P Ebrahimnejad, A Rezaeiroshan… - BioMed Research …, 2023 - Wiley Online Library
Metformin is a multipotential compound for treating diabetes II and controlling hormonal
acne and skin cancer. This study was designed to enhance metformin skin penetration in …