The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits

SZ Shire**i, F Inci - Biotechnology Advances, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles released from various cells, and they can be
found in different bodily fluids. Exosomes have been utilized as biomarkers to diagnose …

An alternative medical diagnosis method: biosensors for virus detection

Y Saylan, Ö Erdem, S Ünal, A Denizli - Biosensors, 2019 - mdpi.com
Infectious diseases still pose an omnipresent threat to global and public health, especially in
many countries and rural areas of cities. Underlying reasons of such serious maladies can …

Aptamer-based point-of-care devices: Emerging technologies and integration of computational methods

Y Aslan, M Atabay, HK Chowdhury, I Göktürk, Y Saylan… - Biosensors, 2023 - mdpi.com
Recent innovations in point-of-care (POC) diagnostic technologies have paved a critical
road for the improved application of biomedicine through the deployment of accurate and …

Smart materials: rational design in biosystems via artificial intelligence

K Sagdic, I Eş, M Sitti, F Inci - Trends in Biotechnology, 2022 - cell.com
Industry 4.0 encompasses a new industrial revolution in which advanced manufacturing
systems are interconnected with information technologies. These sophisticated data …

Carbon‐based nanomaterials and sensing tools for wearable health monitoring devices

Ö Erdem, E Derin, S Zeibi Shire**i… - Advanced Materials …, 2022 - Wiley Online Library
The healthcare system has a drastic paradigm shift from centralized care to home‐based
and self‐monitoring strategies; aiming to reach more individuals, minimize workload in …

Advances in biosensor technologies for acute kidney injury

E Derin, F Inci - ACS sensors, 2021 - ACS Publications
Acute kidney injury (AKI) is one of the most prevalent and complex clinical syndromes with
high morbidity and mortality. The traditional diagnosis parameters are insufficient regarding …

Benchmarking a microfluidic-based filtration for isolating biological particles

F Inci - Langmuir, 2022 - ACS Publications
Isolating particles from complex fluids is a crucial approach in multiple fields including
biomedicine. In particular, biological matrices contain a myriad of distinct particles with …

Unifying the efforts of medicine, chemistry, and engineering in biosensing technologies to tackle the challenges of the COVID-19 pandemic

O Erdem, I Eş, Y Saylan, F Inci - Analytical Chemistry, 2021 - ACS Publications
In the last decades, we have faced several infectious diseases, transiting their statuses from
epidemics to pandemics that affect multiple regions across the globe. As an example …

Microfluidic flow cytometry for blood-based biomarker analysis

Y Zhang, Y Zhao, T Cole, J Zheng, J Guo, SY Tang - Analyst, 2022 - pubs.rsc.org
Flow cytometry has proven its capability for rapid and quantitative analysis of individual cells
and the separation of targeted biological samples from others. The emerging microfluidics …

The host-microbe interplay in human papillomavirus-induced carcinogenesis

R Wakabayashi, Y Nakahama, V Nguyen, JL Espinoza - Microorganisms, 2019 - mdpi.com
Every year nearly half a million new cases of cervix cancer are diagnosed worldwide,
making this malignancy the fourth commonest cancer in women. In 2018, more than 270,000 …