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Advances in the chemistry of redox-active bis (imino) acenaphthenes (BIAN): A case of transition metal complexes
IS Fomenko, NF Romashev, AL Gushchin - Coordination Chemistry …, 2024 - Elsevier
The chemistry of redox-active bis (imino) acenaphthenes (BIAN, R-bian) and metal
complexes based on them has been a rapidly develo** field since the 1990s. The key …
complexes based on them has been a rapidly develo** field since the 1990s. The key …
Metal complexes of thiosemicarbazones for imaging and therapy
JR Dilworth, R Hueting - Inorganica Chimica Acta, 2012 - Elsevier
This review gives an account of the coordination chemistry of thiosemicarbazone ligands
with three (tridentate) or four (tetradentate) potential donor atoms. The syntheses and …
with three (tridentate) or four (tetradentate) potential donor atoms. The syntheses and …
In vitro and in vivo anticancer activity of copper bis (thiosemicarbazone) complexes
D Palanimuthu, SV Shinde… - Journal of medicinal …, 2013 - ACS Publications
Neutral and cationic copper bis (thiosemicarbazone) complexes bearing methyl, phenyl, and
hydrogen, on the diketo-backbone of the ligand have been synthesized. All of them were …
hydrogen, on the diketo-backbone of the ligand have been synthesized. All of them were …
Synthesis, characterization, and in vitro anticancer activity of copper and zinc bis (thiosemicarbazone) complexes
R Anjum, D Palanimuthu, DS Kalinowski… - Inorganic …, 2019 - ACS Publications
A series of eight bis (thiosemicarbazone) ligands and 16 of their respective copper (II) and
zinc (II) complexes containing a combination of hydrogen, methyl, pyridyl, phenyl, and/or …
zinc (II) complexes containing a combination of hydrogen, methyl, pyridyl, phenyl, and/or …
Zinc (II)–thiosemicarbazone complexes are localized to the lysosomal compartment where they transmetallate with copper ions to induce cytotoxicity
As the di-2-pyridylketone thiosemicarbazone (DpT) and 2-acetylpyridine thiosemicarbazone
(ApT) series show potent antitumor activity in vitro and in vivo, we synthesized their …
(ApT) series show potent antitumor activity in vitro and in vivo, we synthesized their …
Hint from an enzymatic reaction: superoxide dismutase models efficiently suppress colorectal cancer cell proliferation
H Lim, C Oh, MS Park, HB Park, C Ahn… - Journal of the …, 2023 - ACS Publications
Superoxide dismutases (SODs) are essential antioxidant enzymes that prevent massive
superoxide radical production and thus protect cells from damage induced by free radicals …
superoxide radical production and thus protect cells from damage induced by free radicals …
[HTML][HTML] Synthesis of carvacrol derivatives as potential new anticancer agent against lung cancer
Lung cancer remains a major public health concern among all cancer diseases due to the
toxicity and side-effects of the available commercially synthesized drugs. Natural product …
toxicity and side-effects of the available commercially synthesized drugs. Natural product …
Mixed ligand copper (II)-diimine complexes of 2-formylpyridine-N 4-phenylthiosemicarbazone: Diimine co-ligands tune the in vitro nanomolar cytotoxicity
Recently, mixed-ligand copper (II) complexes have received much attention in searching for
alternative metallodrugs to cisplatin. A series of mixed ligand Cu (II) complexes of the type …
alternative metallodrugs to cisplatin. A series of mixed ligand Cu (II) complexes of the type …
Synthesis, structure and in vitro pharmacological evaluation of a novel 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (2′-methylbenzoyl) hydrazone bridged copper (II) …
A novel ligand bridged copper (II) coordination polymer,[Cu (HL)(NO3)] n has been
synthesized by reacting 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (2′-methylbenzoyl) …
synthesized by reacting 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (2′-methylbenzoyl) …
Identification of differential anti-neoplastic activity of copper bis (thiosemicarbazones) that is mediated by intracellular reactive oxygen species generation and …
C Stefani, Z Al-Eisawi, PJ Jansson… - Journal of inorganic …, 2015 - Elsevier
Bis (thiosemicarbazones) and their copper (Cu) complexes possess unique anti-neoplastic
properties. However, their mechanism of action remains unclear. We examined the structure …
properties. However, their mechanism of action remains unclear. We examined the structure …