Transgenic hairy roots: recent trends and applications

A Giri, ML Narasu - Biotechnology advances, 2000 - Elsevier
Agrobacterium rhizogenes causes hairy root disease in plants. The neoplastic roots
produced by A. rhizogenes infection is characterized by high growth rate and genetic …

Hairy root culture: a potent method for improved secondary metabolite production of Solanaceous plants

D Biswas, A Chakraborty, S Mukherjee… - Frontiers in Plant …, 2023 - frontiersin.org
Secondary metabolites synthesized by the Solanaceous plants are of major therapeutic and
pharmaceutical importance, many of which are commonly obtained from the roots of these …

Characteristics of heavy metal uptake by plant species with potential for phytoremediation and phytomining

TV Nedelkoska, PM Doran - Minerals engineering, 2000 - Elsevier
Genetically transformed hairy root cultures were established for a range of plant species and
applied in studies of growth and accumulation of heavy metals. Experiments were …

[BOOK][B] Plant cell and tissue culture: a tool in biotechnology

KH Neumann, A Kumar, J Imani - 2009 - Springer
This book is intended to provide a general introduction to this exciting field of plant cell and
tissue culture as tool in biotechnology, without overly dwelling on detailed descriptions of all …

Production of tropane alkaloids in genetically engineered root cultures

T Hashimoto, DJ Yun, Y Yamada - Phytochemistry, 1993 - Elsevier
Hyoscyamine 6β-hydroxylase catalyses the oxidative reactions in the biosynthetic pathway
leading from hyoscyamine to scopolamine. The hydroxylase gene of Hyoscyamus niger was …

Hyperaccumulation of cadmium by hairy roots of Thlaspi caerulescens

TV Nedelkoska, PM Doran - Biotechnology and Bioengineering, 2000 - Wiley Online Library
Hairy roots were used to investigate cadmium uptake by Thlaspi caerulescens, a metal
hyperaccumulator plant with potential applications in phytoremediation and phytomining …

Production of monoclonal antibodies by tobacco hairy roots

R Wongsamuth, PM Doran - Biotechnology and Bioengineering, 1997 - Wiley Online Library
Hairy roots of tobacco (Nicotiana tabacum) were used to produce full‐length murine lgG1
monoclonal antibody. The presence of heavy (γ) and light (κ) chains and fully assembled …

Pneumatically agitated bioreactors in industrial and environmental bioprocessing: hydrodynamics, hydraulics, and transport phenomena

Y Chisti - 1998 - asmedigitalcollection.asme.org
Major aspects of design and operation of pneumatically agitated bioreactors are reviewed.
The focus is on considerations that are relevant to industrial practice. Airlift bioreactors are …

Strategies for enhancing monoclonal antibody accumulation in plant cell and organ cultures

JM Sharp, PM Doran - Biotechnology progress, 2001 - Wiley Online Library
Various strategies aimed at improving IgG1 antibody accumulation in transgenic tobacco
cell and organ cultures were tested. The form of tissue had a significant effect on antibody …

Agrobacterium rhizogenes‐mediated transformation of opium poppy, Papaver somniferum L., and California poppy, Eschscholzia californica Cham., root cultures

SU Park, PJ Facchini - Journal of Experimental Botany, 2000 - academic.oup.com
An efficient protocol for the establishment of transgenic opium poppy (Papaver somniferum
L.) and California poppy (Eschscholzia californica Cham.) root cultures using Agrobacterium …