The discovery of numerous noncoding RNA (ncRNA) transcripts in species from yeast to
mammals has dramatically altered our understanding of cell biology, especially the biology …

The discovery of microRNAs (miRNAs) almost two decades ago established a new
paradigm of gene regulation. During the past ten years these tiny non-coding RNAs have …

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Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

MicroRNAs play important roles in regulating tumour development, progression and
metastasis. Here we show that one of the miR-200 family members, miR-141, is under …

BACKGROUND: Gene expression can be posttranscriptionally regulated by a complex
network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification …

Multiple genetic and epigenetic events characterize tumor progression and define the
identity of the tumors. Advances in high-throughput technologies, like gene expression …

Long non-coding RNAs (lncRNAs) represent an emerging layer of cancer biology,
contributing to tumor proliferation, invasion, and metastasis. Here, we describe a role for the …

EZH2 is the catalytic subunit of the polycomb repressive complex 2 (PRC2), which is a
highly conserved histone methyltransferase that methylates lysine 27 of histone 3 …

Background Epithelial-to-mesenchymal transition (EMT) and aerobic glycolysis are
fundamental processes implicated in cancer metastasis. Although increasing evidence …