Construction of warfarin population pharmacokinetics and pharmacodynamics model in Han population based on Bayesian method

X **a, X Cai, J Chen, S Jiang, J Zhang - Scientific Reports, 2024 - nature.com
The purpose of this paper is to study the genetic polymorphisms of related gene loci
(CYP2C9* 3, VKORC1-1639G> A) based on demographic and clinical factors, and use the …

[HTML][HTML] Percutaneous coronary intervention in the elderly: current updates and trends

MJ Arisha, DA Ibrahim, AA Abouarab, M Rahouma… - Vessel Plus, 2018 - oaepublish.com
Ischemic heart disease is the leading cause of death with acute coronary syndrome
accounting for more than 30% of causes of mortality in the elderly population. The rate of …

[HTML][HTML] Preventing arteriovenous shunt failure in hemodialysis patients: a population‐based cohort study

PY Fan, CC Lee, SH Liu, IJ Li, CH Weng, KH Tu… - Journal of Thrombosis …, 2019 - Elsevier
Essentials• Uncertainty remains about antiplatelets for vascular access patency in
hemodialysis patients.• 95 971 people under hemodialysis were followed in a claims …

The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population

L Bader, A Mahfouz, M Kasem, S Mohammed… - The …, 2020 - nature.com
The objective of this study is to estimate the prevalence of VKORC1, CYP2C9, and CYP4F2
genetic variants and their contribution to warfarin dose variability in Qataris. One hundred …

Assessment of anticoagulation management in outpatients attending a warfarin clinic in Windhoek, Namibia

LJ Jonkman, MP Gwanyanya, MN Kakololo… - Drugs & Therapy …, 2019 - Springer
Background Warfarin, an anticoagulant with a low therapeutic index, requires frequent
international normalized ratio (INR) monitoring to ensure efficacy and safety. Little is known …

Pharmacodynamic Modeling of Warfarin Dosing Algorithm for Cardiovascular Patients in Indonesia: A Tailored Method to Anticoagulation Therapy

NA Putriana, IR Latarissa, T Rusdiana… - Drug Design …, 2025 - Taylor & Francis
Purpose Warfarin is an anticoagulant drug widely used for treating thromboembolism-
related conditions. The main challenge with this drug is the high variability in patients …

Association between VKORC1 gene polymorphism and warfarin dose requirement and frequency of VKORC1 gene polymorphism in patients from Kerman province

MJ Soltani Banavandi, N Satarzadeh - The Pharmacogenomics Journal, 2020 - nature.com
Warfarin is an anticoagulant prescribed in the treatment and prevention of thrombosis.
Variation in dose requirements is different for everyone, and genetic factors have an effect …

Plasma metabolites as predictors of warfarin outcome in atrial fibrillation

AA Bawadikji, CH Teh… - American Journal of …, 2020 - Springer
Background Warfarin is prescribed as an oral anticoagulant to treat/prevent
thromboembolism in conditions such as atrial fibrillation. As there is a narrow therapeutic …

The influence of Javanese turmeric (Curcuma xanthorrhiza) on the pharmacokinetics of warfarin in rats with single and multiple-dose studies

T Rusdiana, YD Mardhiani, NA Putriana… - Pharmaceutical …, 2021 - Taylor & Francis
Context Co-administration between warfarin (WF) and Curcuma xanthorrhiza
Roxb.(Zingiberaceae)(CX) is found in Indonesian patients and need to be evaluated …

To establish a model for the prediction of initial standard and maintenance doses of warfarin for the Han Chinese population based on gene polymorphism: a …

X **a, N Huang, B Li, Y Li, L Zou, D Yuan… - European Journal of …, 2022 - Springer
Purpose The purpose of this paper is to study the correlation between demographic and
clinical factors and warfarin dose of patients in Chinese Han population taking warfarin and …