Stroke in Africa: profile, progress, prospects and priorities

RO Akinyemi, B Ovbiagele, OA Adeniji… - Nature Reviews …, 2021 - nature.com
Stroke is a leading cause of disability, dementia and death worldwide. Approximately 70% of
deaths from stroke and 87% of stroke-related disability occur in low-income and middle …

Impact of Sickle Cell Disease on Affected Individuals in Nigeria: A Critical Review

OP Adigwe, G Onavbavba, SO Onoja - International Journal of …, 2023 - Taylor & Francis
Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Establishing a sickle cell disease registry in Africa: experience from the Sickle Pan-African Research Consortium, Kumasi-Ghana

V Paintsil, EX Amuzu, I Nyanor, E Asafo-Adjei… - Frontiers in …, 2022 - frontiersin.org
Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy,
characterized by painful episodes, anemia, high risk of infection, and other acute and …

Strategies to improve healthcare services for patients with sickle cell disease in Nigeria: The perspectives of stakeholders

H Isa, E Okocha, SA Adegoke… - Frontiers in …, 2023 - frontiersin.org
Background: Sickle cell disease (SCD) continues to pose physical and psychosocial
burdens to patients, caregivers and health workers. Stakeholder engagement in the …

Thalassaemia registries: a call for action. A position statement from the Thalassaemia International Federation

D Farmakis, M Angastiniotis, MM El Ghoul, L Cannon… - …, 2022 - Taylor & Francis
Disease registries can be extremely powerful evidence generating tools while providing a
central meeting point for all implicated stakeholders, facilitating their networking and …

Outcome of Hydroxyurea use in SCD and evaluation of patients' perception and experience in Nigeria

RI Chianumba, AOD Ofakunrin, J Morrice… - Frontiers in …, 2022 - frontiersin.org
Introduction: Hydroxyurea (HU) has been shown to be beneficial in the management of
sickle cell disease (SCD) as it improves treatment outcomes. However, despite the benefits …

[HTML][HTML] Evolving landscape of sickle cell anemia management in Africa: A critical review

HW Musuka, PG Iradukunda, O Mano… - Tropical Medicine and …, 2024 - mdpi.com
Sickle cell disease (SCD) is a prevalent inherited blood disorder, particularly affecting
populations in Africa. This review examined the disease's burden, its diverse clinical …

An implementation trial to m A nage si C kle CEL l dis E ase through inc R eased A dop T ion of hydroxyur E a in Nigeria (ACCELERATE): Study protocol

E Peprah, J Gyamfi, J Patena, H Kayalioglu, T Hameed… - PloS one, 2025 - journals.plos.org
Background Despite the proven efficacy of evidence-based healthcare interventions in
reducing adverse outcomes and mortality associated with Sickle Cell Disease (SCD), a vast …

Skills capacity building for health care services and research through the Sickle Pan African Research Consortium

OE Nnodu, A Osei-Akoto, V Nembaware, J Kent… - Frontiers in …, 2022 - frontiersin.org
Skills development, the building of human capacity, is key to any sustainable capacity
building effort, however, such undertakings require adaptable and tailored strategies. The …

Development of the sickle Pan-African research consortium registry in Tanzania: opportunity to harness data science for sickle cell disease

D Kandonga, RZ Sangeda, U Masamu… - Frontiers in …, 2023 - frontiersin.org
Background Sickle cell disease (SCD) is a severe hereditary form of anemia that contributes
between 50% and 80% of under-five mortality in Africa. Eleven thousand babies are born …