Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …

Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

Genomes of multicellular organisms are characterized by the pervasive expression of
different types of non-coding RNAs (ncRNAs). Long ncRNAs (lncRNAs) belong to a novel …

Here, we present a unifying hypothesis about how messenger RNAs, transcribed
pseudogenes, and long noncoding RNAs" talk" to each other using microRNA response …

Abstract Exosomes are 40–100 nm nano-sized vesicles that are released from many cell
types into the extracellular space. Such vesicles are widely distributed in various body fluids …

Recent reports have described an intricate interplay among diverse RNA species, including
protein-coding messenger RNAs and non-coding RNAs such as long non-coding RNAs …

The first cancer-targeted microRNA (miRNA) drug—MRX34, a liposome-based miR-34
mimic—entered Phase I clinical trials in patients with advanced hepatocellular carcinoma in …

The canonical role of messenger RNA (mRNA) is to deliver protein-coding information to
sites of protein synthesis. However, given that microRNAs bind to RNAs, we hypothesized …

RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of
RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes …

MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways.
These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in …