Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

A hepatocellular carcinoma targeting nanostrategy with hypoxia-ameliorating and photothermal abilities that, combined with immunotherapy, inhibits metastasis and …

T Zhou, X Liang, P Wang, Y Hu, Y Qi, Y **, Y Du… - ACS …, 2020 - ACS Publications
Hepatocellular carcinoma (HCC) is a common and highly malignant tumor that is prone to
recurrence and metastasis and has no effective treatment. Unsurprisingly, its prognosis is …

Ferritin drug carrier (FDC) for tumor targeting therapy

J He, K Fan, X Yan - Journal of Controlled Release, 2019 - Elsevier
Ferritin is an iron storage protein that plays a key role in iron homeostasis and anti-oxidation
of cells. Due to its unique architecture of 24 self-assembling subunits and hollow cavity …

Protein-based nanomedicine for therapeutic benefits of cancer

Q Zhang, J Zhang, J Song, Y Liu, X Ren, Y Zhao - ACS nano, 2021 - ACS Publications
Proteins, a type of natural biopolymer that possess many prominent merits, have been
widely utilized to engineer nanomedicine for fighting against cancer. Motivated by their ever …

Ferritin nanocage: A promising and designable multi-module platform for constructing dynamic nanoassembly-based drug nanocarrier

B Zhang, G Tang, J He, X Yan, K Fan - Advanced Drug Delivery Reviews, 2021 - Elsevier
Ferritin has been widely recognized as an ideal drug delivery vehicle owing to its unique
cage-like structure. Coupled with intrinsic targeting ability and excellent biosafety, ferritin …

Ferritin nanocage based delivery vehicles: From single-, co-to compartmentalized-encapsulation of bioactive or nutraceutical compounds

H Chen, X Tan, X Han, L Ma, H Dai, Y Fu… - Biotechnology Advances, 2022 - Elsevier
Bioactive or nutraceutical ingredients have been widely used in pursuit of health and well-
being. However, the environmental instability, poor solubility and bioavailability, and …

[HTML][HTML] Cell surface GRP78: An emerging imaging marker and therapeutic target for cancer

M Farshbaf, AY Khosroushahi, S Mojarad-Jabali… - Journal of Controlled …, 2020 - Elsevier
As one of the deadliest diseases, cancer frequently resists existing therapeutics because
they do not target all cells within a progressing tumor, for example both tumor stem and …

Chemical factory‐guaranteed enhanced chemodynamic therapy for orthotopic liver cancer

Z Tang, S Wu, P Zhao, H Wang, D Ni, H Li… - Advanced …, 2022 - Wiley Online Library
In the field of nanomedicine, there is a tendency of matching designed nanomaterials with a
suitable type of orthotopic cancer model, not just a casual subcutaneous one. Under this …

Ferritin nanocages: a versatile platform for nanozyme design

C Wang, Q Liu, X Huang, J Zhuang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Nanozymes are a class of nanomaterials with enzyme-like activities and have attracted
increasing attention due to their potential applications in biomedicine. However, nanozyme …