Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation
Over the course of the past half century, the structural elucidation of unknown natural
products has undergone a tremendous revolution. Before World War II, a chemist would …
products has undergone a tremendous revolution. Before World War II, a chemist would …
Simple indole alkaloids and those with a non-rearranged monoterpenoid unit
M Somei, F Yamada - Natural product reports, 2005 - pubs.rsc.org
Simple indole alkaloids and those with a non-rearranged monoterpenoid unit - Natural
Product Reports (RSC Publishing) DOI:10.1039/B316241A Royal Society of Chemistry …
Product Reports (RSC Publishing) DOI:10.1039/B316241A Royal Society of Chemistry …
[PDF][PDF] Mycotoxins, drugs and other extrolites produced by species in Penicillium subgenus Penicillium
JC Frisvad, J Smedsgaard, TO Larsen… - Stud …, 2004 - studiesinmycology.org
The 58 species in Penicillium subgenus Penicillium produce a large number of bioactive
extrolites (secondary metabolites), including several mycotoxins. An overview of these …
extrolites (secondary metabolites), including several mycotoxins. An overview of these …
Synthesis of Oxindoles by Iron-Catalyzed Oxidative 1,2-Alkylarylation of Activated Alkenes with an Aryl C(sp2)H Bond and a C(sp3)H Bond Adjacent to a …
WT Wei, MB Zhou, JH Fan, W Liu… - Angewandte …, 2013 - search.ebscohost.com
Oxindoles are important heterocycles found in a wide range of bioactive natural products
and pharmaceutical molecules.[1, 2] In addition, functionalized oxindoles are versatile …
and pharmaceutical molecules.[1, 2] In addition, functionalized oxindoles are versatile …
Natural products diversity of marine ascidians (Tunicates; Ascidiacea) and successful drugs in clinical development
This present study reviewed the chemical diversity of marine ascidians and their
pharmacological applications, challenges and recent developments in marine drug …
pharmacological applications, challenges and recent developments in marine drug …
Recent applications of the hetero Diels–Alder reaction in the total synthesis of natural products
The synthetic utility and potential power of the Diels–Alder (D–A) reaction in organic
chemistry is evident. These significances have been extended to the synthesis of a plethora …
chemistry is evident. These significances have been extended to the synthesis of a plethora …
Palladium‐Catalyzed Oxidative Difunctionalization of Alkenes with α‐Carbonyl Alkyl Bromides Initiated through a Heck‐type Insertion: A Route to Indolin‐2‐ones
JH Fan, WT Wei, MB Zhou, RJ Song… - Angewandte Chemie, 2014 - Wiley Online Library
The oxidative interception of various σ‐alkyl palladium (II) intermediates with additional
reagents for the difunctionalization of alkenes is an important research area. A new …
reagents for the difunctionalization of alkenes is an important research area. A new …
New Communesin Derivatives from the Fungus Penicillium sp. Derived from the Mediterranean Sponge Axinella verrucosa
R Jadulco, RA Edrada, R Ebel, A Berg… - Journal of Natural …, 2004 - ACS Publications
The ethyl acetate extract of Penicillium sp., derived from the Mediterranean sponge Axinella
verrucosa, yielded the known compound communesin B (1) and its new congeners …
verrucosa, yielded the known compound communesin B (1) and its new congeners …
Dearomatization of 3-Nitroindoles Enabled Using Palladium-Catalyzed Decarboxylative [4+ 2] Cycloaddition of 2-Alkylidenetrimethylene Carbonates
PH Dou, SP Yuan, Y Chen, JQ Zhao… - The Journal of …, 2022 - ACS Publications
A dearomatization process of 3-nitroindoles enabled using palladium-catalyzed
decarboxylative [4+ 2] cycloaddition of either 2-alkylidenetrimethylene carbonates or 2 …
decarboxylative [4+ 2] cycloaddition of either 2-alkylidenetrimethylene carbonates or 2 …
Recent advances on the total syntheses of communesin alkaloids and perophoramidine
BM Trost, M Osipov - Chemistry–A European Journal, 2015 - Wiley Online Library
The communesin alkaloids are a diverse family of Penicillium‐derived alkaloids. Their
caged‐polycyclic structure and intriguing biological profiles have made these natural …
caged‐polycyclic structure and intriguing biological profiles have made these natural …