Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation

KC Nicolaou, SA Snyder - Angewandte Chemie International …, 2005 - Wiley Online Library
Over the course of the past half century, the structural elucidation of unknown natural
products has undergone a tremendous revolution. Before World War II, a chemist would …

Simple indole alkaloids and those with a non-rearranged monoterpenoid unit

M Somei, F Yamada - Natural product reports, 2005 - pubs.rsc.org
Simple indole alkaloids and those with a non-rearranged monoterpenoid unit - Natural
Product Reports (RSC Publishing) DOI:10.1039/B316241A Royal Society of Chemistry …

[PDF][PDF] Mycotoxins, drugs and other extrolites produced by species in Penicillium subgenus Penicillium

JC Frisvad, J Smedsgaard, TO Larsen… - Stud …, 2004 - studiesinmycology.org
The 58 species in Penicillium subgenus Penicillium produce a large number of bioactive
extrolites (secondary metabolites), including several mycotoxins. An overview of these …

Synthesis of Oxindoles by Iron-Catalyzed Oxidative 1,2-Alkylarylation of Activated Alkenes with an Aryl C(sp2)H Bond and a C(sp3)H Bond Adjacent to a …

WT Wei, MB Zhou, JH Fan, W Liu… - Angewandte …, 2013 - search.ebscohost.com
Oxindoles are important heterocycles found in a wide range of bioactive natural products
and pharmaceutical molecules.[1, 2] In addition, functionalized oxindoles are versatile …

Natural products diversity of marine ascidians (Tunicates; Ascidiacea) and successful drugs in clinical development

SK Palanisamy, NM Rajendran, A Marino - Natural products and …, 2017 - Springer
This present study reviewed the chemical diversity of marine ascidians and their
pharmacological applications, challenges and recent developments in marine drug …

Recent applications of the hetero Diels–Alder reaction in the total synthesis of natural products

MM Heravi, T Ahmadi, M Ghavidel, B Heidari… - RSC advances, 2015 - pubs.rsc.org
The synthetic utility and potential power of the Diels–Alder (D–A) reaction in organic
chemistry is evident. These significances have been extended to the synthesis of a plethora …

Palladium‐Catalyzed Oxidative Difunctionalization of Alkenes with α‐Carbonyl Alkyl Bromides Initiated through a Heck‐type Insertion: A Route to Indolin‐2‐ones

JH Fan, WT Wei, MB Zhou, RJ Song… - Angewandte Chemie, 2014 - Wiley Online Library
The oxidative interception of various σ‐alkyl palladium (II) intermediates with additional
reagents for the difunctionalization of alkenes is an important research area. A new …

New Communesin Derivatives from the Fungus Penicillium sp. Derived from the Mediterranean Sponge Axinella verrucosa

R Jadulco, RA Edrada, R Ebel, A Berg… - Journal of Natural …, 2004 - ACS Publications
The ethyl acetate extract of Penicillium sp., derived from the Mediterranean sponge Axinella
verrucosa, yielded the known compound communesin B (1) and its new congeners …

Dearomatization of 3-Nitroindoles Enabled Using Palladium-Catalyzed Decarboxylative [4+ 2] Cycloaddition of 2-Alkylidenetrimethylene Carbonates

PH Dou, SP Yuan, Y Chen, JQ Zhao… - The Journal of …, 2022 - ACS Publications
A dearomatization process of 3-nitroindoles enabled using palladium-catalyzed
decarboxylative [4+ 2] cycloaddition of either 2-alkylidenetrimethylene carbonates or 2 …

Recent advances on the total syntheses of communesin alkaloids and perophoramidine

BM Trost, M Osipov - Chemistry–A European Journal, 2015 - Wiley Online Library
The communesin alkaloids are a diverse family of Penicillium‐derived alkaloids. Their
caged‐polycyclic structure and intriguing biological profiles have made these natural …