The use of systemic anticancer chemotherapy is intrinsically limited by its toxicity. Whether
dealing with small molecules or biopharmaceuticals, after systemic administration, small …

Polymeric nanoparticles (NPs) are a promising platform for medical applications in drug
delivery. However, their use as drug carriers is limited by biological (eg, immunological) …

ATP-binding cassette (ABC) transporters are involved in active pum** of many diverse
substrates through the cellular membrane. The transport mediated by these proteins …

Abstract Poly (lactic‐co‐glycolic) acid (PLGA) is one of the most versatile biomedical
polymers, already approved by regulatory authorities to be used in human research and …

The development of therapeutic cancer vaccines as a means to generate immune reactivity
against tumors has been explored since the early discovery of tumor-specific antigens by …

Although nanomedicine has been highly investigated for cancer treatment over the past
decades, only a few nanomedicines are currently approved and in the market; making this …

Recent advances in nanotechnology have contributed tremendously to the development
and revolutionizing of drug delivery systems in the field of nanomedicine. In particular …

The aim of the present study was to optimize lorazepam loaded PLGA nanoparticles (Lzp‐
PLGA‐NPs) by investigating the effect of process variables on the response using Box …

Albumin is a promising surface modifier of nanoparticulate drug delivery systems. Serving as
a dysopsonin, albumin can protect circulating nanoparticles (NPs) from the recognition and …

Numerous human disorders can benefit from targeted, intravenous (IV) drug delivery.
Polymeric nanoparticles have been designed to undergo systemic circulation and deliver …