Intracellular cAMP sensor EPAC: physiology, pathophysiology, and therapeutics development
WG Robichaux III, X Cheng - Physiological reviews, 2018 - journals.physiology.org
This review focuses on one family of the known cAMP receptors, the exchange proteins
directly activated by cAMP (EPACs), also known as the cAMP-regulated guanine nucleotide …
directly activated by cAMP (EPACs), also known as the cAMP-regulated guanine nucleotide …
Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance
Astrocytes may function as mediators of the impact of noradrenaline on neuronal function.
Activation of glial α1-adrenergic receptors triggers rapid astrocytic Ca2+ elevation and …
Activation of glial α1-adrenergic receptors triggers rapid astrocytic Ca2+ elevation and …
The principle of conformational signaling
P Tompa - Chemical Society Reviews, 2016 - pubs.rsc.org
Signal transduction is the primary process by which cells respond to changes in their
physical and chemical environments. Cellular response is initiated through a signaling …
physical and chemical environments. Cellular response is initiated through a signaling …
Absolute measurement of cellular activities using photochromic single-fluorophore biosensors and intermittent quantification
F Bierbuesse, AC Bourges, V Gielen… - Nature …, 2022 - nature.com
Genetically-encoded biosensors based on a single fluorescent protein are widely used to
visualize analyte levels or enzymatic activities in cells, though usually to monitor relative …
visualize analyte levels or enzymatic activities in cells, though usually to monitor relative …
Concentration dependence of Förster resonant energy transfer between donor and acceptor nanocrystal quantum dot layers: Effect of donor-donor interactions
M Lunz, AL Bradley, VA Gerard, SJ Byrne… - Physical Review B …, 2011 - APS
The influences of donor and acceptor concentrations on Förster resonant energy transfer
(FRET) in a separated donor-acceptor quantum dot bilayer structure have been investigated …
(FRET) in a separated donor-acceptor quantum dot bilayer structure have been investigated …
From intracellular signaling to population oscillations: bridging size‐and time‐scales in collective behavior
Collective behavior in cellular populations is coordinated by biochemical signaling networks
within individual cells. Connecting the dynamics of these intracellular networks to the …
within individual cells. Connecting the dynamics of these intracellular networks to the …
Energy transfer from an individual silica nanoparticle to graphene quantum dots and resulting enhancement of photodetector responsivity
Förster resonance energy transfer (FRET), referred to as the transfer of the photon energy
absorbed in donor to acceptor, has received much attention as an important physical …
absorbed in donor to acceptor, has received much attention as an important physical …
Knowledge-based design of long-chain arylpiperazine derivatives targeting multiple serotonin receptors as potential candidates for treatment of autism spectrum …
E Lacivita, M Niso, M Mastromarino… - ACS Chemical …, 2021 - ACS Publications
Autism spectrum disorder (ASD) includes a group of neurodevelopmental disorders
characterized by core symptoms such as impaired social interaction and communication …
characterized by core symptoms such as impaired social interaction and communication …
H2O2-mediated modulation of cytosolic signaling and organelle function in rat hippocampus
FJ Gerich, F Funke, B Hildebrandt, M Faßhauer… - … -European Journal of …, 2009 - Springer
Reactive oxygen species (ROS) released from (dys-) functioning mitochondria contribute to
normal and pathophysiological cellular signaling by modulating cytosolic redox state and …
normal and pathophysiological cellular signaling by modulating cytosolic redox state and …
Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT7 receptor low-basicity agonists, potential neuropathic painkillers
The 5-HT 7 receptor has recently gained much attention due to its involvement in multiple
physiological functions and diseases. The insufficient quality of the available molecular …
physiological functions and diseases. The insufficient quality of the available molecular …